Analyse und Sortierung von im Fluss befindlichen biologischen Zellen

Details

Veröffentlichungs-Nr.

EP2602608

Aktenzeichen

EP12166436

Anmeldetag

2. Mai 2012

Veröffentlichung

14. September 2016

Erteilung

14. September 2016

Rechtsraum

EP

IPC

G01N15/14// G03H1/00

Abstract

A device (1) for sorting biological cell(s) immersed in a flowing medium is described. The device comprises a holographic imaging unit comprising a plurality of holographic imaging elements (2), a fluid handling unit comprising a plurality of microfluidic channels (3) for conducting flowing medium along a corresponding holographic imaging element (2) and comprising a microfluidic switch (5) arranged downstream of an imaging region in the microfluidic channel for controllably directing each biological cell in the flowing medium into a selected one of a plurality of outlets (6). The device also comprises a processing unit (7) adapted for real-time characterization of the holographic diffraction image obtained for each of the biological cells thereby taking into account at least one predetermined biological cell type signature. The processing unit (7) furthermore is adapted for controlling the microfluidic switch (5) in response to said characterization.

Anmelder

Firma

IMEC

Land

🇧🇪 Belgien

Fachgebiete