Herstellung von 1-substitutierten 3-Fluoralkyl-pyrazol-4-carboxylsäure-Estern

Details

Veröffentlichungs-Nr.

EP2671874

Aktenzeichen

EP12171097

Anmeldetag

6. Juni 2012

Veröffentlichung

13. Januar 2016

Erteilung

13. Januar 2016

Rechtsraum

EP

IPC

C07D231/14

Abstract

Process for the manufacture of an ester or the respective free acid of a 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acid of formula (I) wherein - Y is H, F or an alkyl group having from 1 to 12 carbon atoms which is optionally substituted by at least one halogen atom, an aralkyl group or an aryl group, - R 1 is H or an organic residue, - R 2 is H or an organic residue, which comprises submitting a compound of formula (II) wherein Y is as defined above - X is Cl, Br or I, - R 1 ' is H or an organic residue, - R 2 ' is H or an organic residue, to a reduction reaction using a hydrogen donating compound in the presence of UV light. The compounds of formula (I) are useful e.g. as intermediates for pharmaceuticals and agrochemicals.

Anmelder

Firma

SOLVAY SA

Land

🇧🇪 Belgien

Fachgebiete