Biomarker für die Krankheit "complex regional pain syndrome" (CRPS)

Details

Veröffentlichungs-Nr.

EP2816354

Aktenzeichen

EP13172634

Anmeldetag

19. Juni 2013

Veröffentlichung

28. September 2016

Erteilung

28. September 2016

Rechtsraum

EP

IPC

G01N33/564G01N33/68

Abstract

The present invention relates in a first aspect to a method for diagnosing the presence or the risk of development or the therapy control of Complex Regional Pain Syndrome (CRPS) or other types of inflammatory diseases involving joints. The method comprises the steps of analyzing a sample from an individual to be tested for the presence of autoantibodies against p29ING4 whereby the presence of said autoantibodies against an ING gene product, in particular, against p29ING4 is indicative for the presence or the risk of development of the therapy control of CRPS or other types of inflammatory diseases involving joints. In another aspect, the present invention relates to a diagnostic kit for use in the method according to the present invention. Further, the present application relates to the use of ING gene production, in particular, of p29ING4 or immunoreactive peptides thereof in the diagnosis, risk assessment or therapy control of CRPS or developing CRPS or other types of inflammatory diseases involving joints, in particular, in subjects undergoing surgery of hands and feet or after bone fractures of hands and feet.

Anmelder

Firma

Medizinische Hochschule Hannover

Land

🇩🇪 Deutschland

Fachgebiete