Verfahren zur Identifizierung der Monoisotopischen Masse von Spezien von Molekülen

Details

Veröffentlichungs-Nr.

EP3293755

Aktenzeichen

EP17174330

Anmeldetag

2. Juni 2017

Veröffentlichung

22. Mai 2019

Erteilung

22. Mai 2019

Rechtsraum

EP

IPC

H01J49/00

Abstract

The invention concerns a method for identification of the monoisotopic mass or a parameter correlated the mass of the isotopes of the isotope distribution of at least one species of molecules contained in a sample and/or originated from a sample by at least an ionisation process. The method is comprising the following steps: (i) measuring a mass spectrum of the sample with a mass spectrometer (ii) dividing at least one range of measured m/z values of the mass spectrum of the sample into fractions (iii) assigning at least some of the fractions of the at least one range of measured m/z values to one processor of several provided processors (iv) deducing for each of the at least one species of molecules contained in the sample and/or originated from the sample from the measured mass spectrum in at least one of the fractions of the at least one range of measured m/z values an isotope distribution of their ions having a specific charge z (v) deducing from at least one deduced isotope distribution of the ions of each of the at least one species of molecules contained in the sample and/or originated from the sample the monoisotopic mass or a parameter correlated the mass of the isotopes of the isotope distribution of the species of molecules.

Anmelder

Firma

Thermo Fisher Scientific (Bremen) GmbH

Land

🇩🇪 Deutschland

Fachgebiete