Ss-Aminosäurederivat, Kinaseinhibitor und Pharmazeutische Zusammensetzung damit und Verwendung davon

Details

Veröffentlichungs-Nr.

EP3845276

Aktenzeichen

EP20213242

Anmeldetag

10. Dezember 2020

Veröffentlichung

29. Januar 2025

Erteilung

29. Januar 2025

Rechtsraum

EP

IPC

A61P27/06C07D231/12C07D231/18C07D403/12A61K31/415

Abstract

A compound represented by Formula (I), a pharmaceutically acceptable salt or ester, hydrate, solvate or crystalline form thereof is provided: <img class="EMIRef" id="708644550-ia01" /> The compound represented by Formula (I) is a β-amino acid derivative, and in Formula (I): X is a single bond or O; Y is NH or C=O; Z is C=O, C=S, NH, <img class="EMIRef" id="708644550-ia02" /> <img class="EMIRef" id="708644550-ia03" /> W is C or N; A is a single bond, O, OH, OCH<2>, a heterocycle or N<3>; R<1> is H or F; R<2> is H, F, OH, CF<3>, CH<2>OH, CHO or <img class="EMIRef" id="708644550-ia04" /> ; R<3> is H; n is 0 or 1; and m is 0 or 1.

Anmelder

Firma

Industrial Technology Research Institute

Land

🇹🇼 Taiwan

Fachgebiete