Neuromodulationsbasiertes Adaptives Steuergerät für Mitralstenose

Details

Veröffentlichungs-Nr.

EP3858247

Aktenzeichen

EP21151607

Anmeldetag

14. Januar 2021

Veröffentlichung

22. Oktober 2025

Erteilung

22. Oktober 2025

Rechtsraum

EP

IPC

A61B8/06A61B5/00A61B5/02G16H50/50

Abstract

This disclosure provides a simulation platform to study and perform predictive analysis on valvular heart disease, Mitral stenosis (MS) and provides a control approach to correct hemodynamic imbalances during MS conditions. Conventional approaches of valve repair or replacement are often associated with risk of thromboembolism, need for anticoagulation, prosthetic endocarditis, and impaired left ventricle function. The cardiovascular hemodynamics model of the present disclosure helps to create 'what if conditions to study variations in different hemodynamic parameters like blood flow, aortic and ventricular pressure, etc. during normal and pathological conditions. An adaptive control system in conjunction with the hemodynamic cardiovascular system (CVS) is provided to handle hemodynamic disbalance during moderate to severe MS conditions. The adaptive controller is hypothesized in line with the neuromodulation approach and modulates left ventricular contractility and vagal tone to counter the symptoms associated with MS.

Anmelder

Firma

Tata Consultancy Services Limited

Land

🇮🇳 Indien

Fachgebiete