Substituierte Vicinale Diaminverbindungen und deren Verwendung zur Behandlung, Linderung oder Vorbeugung von Schmerzen

Details

Veröffentlichungs-Nr.

EP3964497

Aktenzeichen

EP20194568

Anmeldetag

4. September 2020

Veröffentlichung

9. März 2022

Rechtsraum

EP

IPC

C07C275/24C07C275/26C07D333/74A61P25/36A61K31/36

Abstract

The present invention relates to a compound of the following formula (I) or (II), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof:The invention furthermore relates to a pharmaceutical composition comprising the compound having formula (I) or (II) and optionally one or more pharmaceutically acceptable excipient(s) and/or carrier(s), as well as to these compounds for use in the treatment, amelioration or prevention of pain, opioid overdose, addictions, neuropsychiatric disorders, Prader-Willi Syndrome, gastrointestinal disorders, skin disorders, dyspnea, headache and/or temporomandibular joint dysfunction, including methods of treating, ameliorating or preventing pain involving administering to a patient in need thereof an effective amount of the compound having formula (I) or (II).

Anmelder

Firma

Friedrich-Alexander-Universität Erlangen-Nürnberg

Land

🇩🇪 Deutschland

Fachgebiete