Verfahren zur Behandlung von Medizinischen Metallen und deren Legierungen

Details

Veröffentlichungs-Nr.

EP4049690

Aktenzeichen

EP21159240

Anmeldetag

25. Februar 2021

Veröffentlichung

14. August 2024

Erteilung

14. August 2024

Rechtsraum

EP

IPC

A61L31/02A61L31/08A61L31/14

Abstract

The method for treatment metals and metal alloys used for implants, especially vascular stents, is provided. The method comprises of three combined steps, including the first plasma-treatment step, the hydrothermal treatment and the second plasma-treatment step. The first plasma-treatment step assures for a contaminant-free surface with high surface energy, which in turn enables nucleation sites of appropriate properties for depositing a nano-structured film of titanium oxide. The next step is the deposition of a titanium oxide film. The second step is preferably performed within 10 to 1000 s after the first plasma treatment to minimise the risk of spontaneous hydrophobic recovery. The as-deposited materials are further treated by the second plasma treatment, which assures for appropriate surface finish and crystallinity of the thin nano-structured titanium oxide film. The methods of invention enable the formation of the titanium oxide layer on the surface of metals or alloys with improved biocompatibility/hemocompatibility against state of the art.

Anmelder

Firma

Jozef Stefan Institute

Land

🇸🇮 Slowenien

Fachgebiete