Anti-Obesitas und Antidiabetische Wirkung Bromierter Diterpene aus Roten Algen der Gattung Laurencia und Anwendungen davon
EP4556003
Art A1
21. Mai 2025
Anmelder: National and Kapodistrian University of Athens, Special Account for Research Funds of University of Crete (SARF UoC) 🇬🇷
Details
- Veröffentlichungs-Nr.
- EP4556003
- Aktenzeichen
- EP23386117
- Anmeldetag
- 16. November 2023
- Veröffentlichung
- 21. Mai 2025
- Rechtsraum
- EP
- IPC
- A61K31/047A61K9/00A61K31/133A61K47/00A61P3/00A61P3/04
Abstract
The present invention discloses a method of treatment and/or prevention of obesity using a composition comprising of brominated diterpenes from red algae of the genus Laurencia as active ingredients and preferably the diterpene neorogioldiol, isolated from Laurencia sp. or chemically synthesized. The said diterpenes suppress pre-adipocyte differentiation to adipocytes, modulate metabolism in 3T3-L1 cells, restrict weight gain and development of glucose intolerance when administered intraperitoneally in vivo, in the mouse model of high fat diet-induced obesity.
Anmelder
- Firmen
- National and Kapodistrian University of Athens
Special Account for Research Funds of University of Crete (SARF UoC) - Land
- 🇬🇷 Griechenland