Bindemittel mit Veränderten Fc-Vermittelten Effektorfunktionen

Details

Veröffentlichungs-Nr.

EP4644413

Aktenzeichen

EP24174150

Anmeldetag

3. Mai 2024

Veröffentlichung

5. November 2025

Rechtsraum

EP

IPC

C07K16/00C07K16/28

Abstract

The present invention relates to CH3 domain-containing binding agents, such as antibodies, that have altered Fc-mediated effector functions resulting from one or more amino acid modifications in the Fc domain. The invention further relates to polynucleotides encoding such binding agents, cells capable of producing such binding agents and the use of the binding agents of the invention for the treatment of diseases.

Anmelder

Firma

Genmab B.V.

Land

🇳🇱 Niederlande

Fachgebiete