Rekombinantes Menschen-/rinder-Parainfluenzavirus 3 (B/HPIV3) mit Expression eines Chimären RSV/BPIV3-F-Proteins und Verwendungen davon
Anmelder: The United States of America, as represented by the Secretary, Department of Health and Human Services 🇺🇸
Details
- Veröffentlichungs-Nr.
- EP4714464
- Anmeldetag
- 20. Januar 2016
- Veröffentlichung
- 25. März 2026
- Rechtsraum
- EP
- IPC
- A61K39/12
Abstract
Recombinant paramyxoviruses including a viral genome encoding a heterologous gene are provided. In several embodiments, the recombinant paramyxovirus is a recombinant parainfluenza virus, such as a recombinant PIV3 including a viral genome encoding a heterologous respiratory syncytial virus F ectodomain linked to the transmembrane domain and the cytoplasmic tail of the F protein from the PIV3. Nucleic acid molecules including the genome of a recombinant paramyxoviruses are also provided. The recombinant viruses may advantageously be used in vaccine formulations, such as for vaccines against parainfluenza virus and respiratory syncytial virus.
Anmelder
- Firma
- The United States of America, as represented by the Secretary, Department of Health and Human Services
- Land
- 🇺🇸 USA
US-Bundesministerium, das über seine Behörden (u.a. NIH) medizinische Forschung fördert und daraus resultierende Patente im Namen der US-Regierung hält.
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