Verwendung von Dampfabgeschiedenen Durchflusspfaden zur Verbesserung der Chromatographie von Metall-Interaktiven Analyten

Details

Veröffentlichungs-Nr.

EP4721878

Anmeldetag

18. September 2018

Veröffentlichung

8. April 2026

Rechtsraum

EP

IPC

B05D1/00(RESTEK CORP et al.)(HEWLETT PACKARD CO et al.)

Abstract

A device for separating analytes is disclosed. The device has a sample injector, sample injection needle, sample reservoir container in communication with the sample injector, chromatography column downstream of the sample injector, and fluid conduits connecting the sample injector and the column. The interior surfaces of the fluid conduits, sample injector, sample reservoir container, and column form a flow path having wetted surfaces. A portion of the wetted surfaces of the flow path are coated with an alkylsilyl coating that is inert to at least one of the analytes. The alkylsilyl coating has the Formula I: <img class="EMIRef" id="37759093-cfc3-4bcf-87b1-737cff9b804e-ia01" /> R<1>, R<2>, R<3>, R<4>, R<5>, and R<6> are each independently selected from (C<1>-C<6>)alkoxy, -NH(C<1>-C<6>)alkyl, -N((C<1>-C<6>)alkyl)<2>, OH, OR<A>, and halo. R<A> represents a point of attachment to the interior surfaces of the fluidic system. At least one of R<1>, R<2>, R<3>, R<4>, R<5>, and R<6> is OR<A>. X is (C<1>-C<20>)alkyl, -O[(CH<2>)<2>O]<1-20>-, -(C<1>-C<10>)[NH(CO)NH(C<1>-C<10>)]<1-20>-, or -(C<1>-C<10>)[alkylphenyl(C<1>-C<10>)alkyl]<1-20>-.

Anmelder

Firma

Waters Technologies Corporation

Land

🇺🇸 USA