Verfahren und Zusammensetzungen zur In-Situ-Synchronisierung von Reaktionen

Details

Veröffentlichungs-Nr.

EP4741513

Anmeldetag

29. Juli 2022

Veröffentlichung

13. Mai 2026

Rechtsraum

EP

IPC

C12Q1/6853, C12Q1/6841C12Q1/6841(OMNIOME INC et al.)

Abstract

The present disclosure in some aspects relates to methods and compositions for accurately detecting and quantifying multiple analytes present in a biological sample. In some aspects, the methods and compositions provided herein address issues associated with the heterogeneity of analyte abundance (e.g., gene expression levels) and variations among reactions at different locations of a sample (e.g., amplification reaction starting earlier at one location than another location). In some aspects, a method disclosed herein provides a tighter distribution of signal spot size and intensity in a sample, as compared to methods that result in a wide and heterogeneous size and intensity distribution of signal spots.

Anmelder

Firma

10X Genomics, Inc.

Land

🇺🇸 USA

Fachgebiete