Zellanalyse mit Chemfet-Sensor-Array-Systemen

Details

Veröffentlichungs-Nr.

EP4752544

Anmeldetag

11. September 2019

Veröffentlichung

3. Juni 2026

Rechtsraum

EP

IPC

G01N27/414, G01N33/487G01N33/487

Abstract

Various cell analysis systems of the present teachings can measure the electrical and metabolic activity of single, living cells with subcellular addressability and simultaneous data acquisition for between about 10 cells to about 500,000 cells in a single analysis. Various sensor array devices of the present teachings can have sensor arrays with between 20 million to 660 million ChemFET sensors built into a massively paralleled array and can provide for simultaneous measurement of cells with data acquisition rates in the kilohertz (kHz) range. As various ChemFET sensor arrays of the present teachings can detect chemical analytes as well detect changes in cell membrane potential, various cell analysis systems of the present teachings also provide for the controlled chemical and electrical interrogation of cells. The frame rate can be increased by selecting a smaller subset of pixels to monitor, i.e. by windowing down the area of a sensor array device over which data is collected.

Anmelder

Firma

Life Technologies Corporation

Land

🇺🇸 USA