Toll-Like-Rezeptoragonisten und Verwendung davon

EP4756029 13. Februar 2025

Anmelder: Haichang Biotech Co., Ltd. 🇨🇳

Details

Veröffentlichungs-Nr.
EP4756029
Anmeldetag
9. August 2024
Veröffentlichung
13. Februar 2025
Rechtsraum
EP
Offizieller Volltext

Abstract

Disclosed is a Toll-like receptor agonist, which is a Class C CpG-ODN that can effectively activate TLR9. Its nucleotide sequence comprises any one of the modified or unmodified nucleotide sequences set forth in SEQ ID NOs: 1-4. The Toll-like receptor agonist has a significant effect in inhibiting tumor growth. The lipid-encapsulated Toll-like receptor agonist provided can inhibit tumor growth, prevent tumor recurrence, and improve immune activation efficiency alone or in combination with an additional therapeutic agent, and exhibits improved performance compared to free Toll-like receptor agonists.

Anmelder

Firma
Haichang Biotech Co., Ltd.
Land
🇨🇳 China

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