Magnetresonanzspektroskopiesystem und Verfahren zur Diagnose von Schmerzen oder Infektionen im Zusammenhang mit Propionsäure
Anmelder: Aclarion, Inc., The Regents of the University of California 🇺🇸
Details
- Veröffentlichungs-Nr.
- EP4772108
- Anmeldetag
- 16. Juni 2017
- Veröffentlichung
- 8. Juli 2026
- Rechtsraum
- EP
- IPC
- A61B5/00
Abstract
An MR Spectroscopy (MRS) system and approach is provided for measuring spectral information corresponding with propionic acid (PA), either alone or in combination with other measurements corresponding with other chemicals, to diagnose and/or monitor at least one of bacterial infection, such as associated with P. acnes, or conditions related thereto such as nociceptive pain associated with tissue acidity. An interfacing DDD-MRS signal processor receives output signals to produce a post-processed spectrum, with spectral regions corresponding with certain chemicals, including PA, then measured as biomarkers. A diagnostic processor derives a diagnostic value for each disc, and performs certain normalizations, based upon ratios of the spectral regions related to chemicals implicated in degenerative painful tissue pathology, such as PA and hypoxia markers of lactic acid (LA) and alanine (AL), and structural chemicals of proteoglycan (PG) and collagen or carbohydrate (CA).
Anmelder
- Firmen
- Aclarion, Inc.
The Regents of the University of California - Land
- 🇺🇸 USA
US-amerikanisches öffentliches Universitätssystem mit zahlreichen Standorten (u.a. Berkeley, Los Angeles, San Diego). Die Regents of the University of California halten die Patente aus Forschung in Biotechnologie, Medizin, Materialwissenschaften und Ingenieurwesen.
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Vertreten von
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Hoffmann Eitle
Hoffmann Eitle · München