Metabolisch Optimierte Zellkultur
Anmelder: Regeneron Pharmaceuticals, Inc. 🇺🇸
Details
- Veröffentlichungs-Nr.
- EP4772614
- Anmeldetag
- 10. Oktober 2014
- Veröffentlichung
- 8. Juli 2026
- Rechtsraum
- EP
- IPC
- C12N5/16
Abstract
An improved method for large scale production of proteins and/or polypeptides in cell culture is provided. In accordance with the present invention, the method provides for culturing cells that have metabolically shifted. The use of such a method or system allows high levels of protein or polypeptide production and reduces accumulation of unwanted metabolic waste such as lactate. Proteins and polypeptides expressed in accordance with the present invention may be advantageously used in the preparation of pharmaceutical, immunogenic, or other commercial biologic compositions, such as antibodies.
Anmelder
- Firma
- Regeneron Pharmaceuticals, Inc.
- Land
- 🇺🇸 USA
US-amerikanisches Biotechnologieunternehmen mit Sitz in Tarrytown, New York. Es entwickelt biopharmazeutische Wirkstoffe, unter anderem monoklonale Antikörper zur Behandlung von Augen-, Immun- und Krebserkrankungen.
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