Korallin-Hydroxyapatit und Herstellungsverfahren und Verwendung davon

Details

Veröffentlichungs-Nr.

EP4775230

Anmeldetag

13. September 2025

Veröffentlichung

15. Juli 2026

Rechtsraum

EP

Abstract

The present disclosure provides a coralline hydroxyapatite having a pore size of 30 µm to 1300 µm, a porosity of 50% to 70%, and a conversion rate of 50% or more, and a preparation method and use thereof. The preparation method comprises: soaking pretreated corallite in a cutting protective agent, and then cutting to obtain cut corallite, and screening for cut corallite that meets a cutting size requirement to obtain an acceptable product of cut corallite; fully soaking the acceptable product of cut corallite in a phosphate solution, and performing a hydrothermal exchange reaction to obtain the coralline hydroxyapatite; wherein the cutting protective agent is a solution containing a polyol. The preparation method of the present disclosure can significantly improve the cutting efficiency, broaden the cutting specifications and sizes, and significantly improve the yield of acceptable product, especially the yield of acceptable small-size products, which further broadens the application range of artificial bones.

Anmelder

Firma

WitKang Zhiyuan Medical Devices (Xi'an) Co., Ltd.

Land

🇨🇳 China