Injizierbares Hydrogel zur Abgabe Osteogener Substanzen

Details

Veröffentlichungs-Nr.

EP4775232

Anmeldetag

8. Juli 2024

Veröffentlichung

15. Juli 2026

Rechtsraum

EP

IPC

A61L27/54

Abstract

The invention relates to an injectable hydrogel composition of about 5-20 wt% gelatin, about 0.5-2 wt% hyaluronic acid, about 0.5-1.0 wt% genipin and an aqueous medium. The composition exhibits high biocompatibility, injectability and in-situ gelation ability at bone defect sites. The composition is suitable for serving as an osteogenic scaffold for cell adhesion and as an osteogenic carrier for delivering beneficial substance for promoting bone regeneration. The invention also relates to a medical formulation comprising the injectable hydrogel composition in combination with an osteogenic substance, as well as said formulation for use in medicine and especially in the treatment of segmental bone defect.

Anmelder

Firma

Taipei Medical University

Land

🇹🇼 Taiwan

Fachgebiete