Lösung zur Sequenzierung der Chipreinigung, Sequenzierungsverfahren und Kit

Details

Veröffentlichungs-Nr.

EP4796646

Anmeldetag

12. Februar 2026

Veröffentlichung

26. August 2026

Rechtsraum

EP

IPC

C12Q1/6874

Abstract

The present application provides a solution for sequencing chip cleaning, a sequencing method, and a kit. The solution for sequencing chip cleaning includes a basic buffer, Na⁺ and/or K⁺, a surfactant, and a pH regulator. The solution further comprises at least one of a divalent cation, NH₄⁺, and a polymerase. In the solution for sequencing chip cleaning provided herein, at least one of a divalent cation, NH₄⁺, and a polymerase is further added on the basis of the basic buffer, Na⁺ and/or K⁺, the surfactant, and the pH regulator, such that, after a sequencing chip is cleaned by using the solution, the solution remaining on the sequencing chip can play a buffering role and provide a stable reaction environment for the incorporation of nucleotides or nucleotide analogs into nucleic acid templates when the sequencing chip is used for sequencing, thereby improving the reaction efficiency of incorporating nucleotides or nucleotide analogs into nucleic acid templates, further reducing the phasing, and improving the sequencing accuracy.

Anmelder

Firma

GeneMind Biosciences Company Limited

Land

🇨🇳 China

Fachgebiete