Verkapselte Zusammensetzungen zur Zahn- und Knochenremineralisierung

Details

Veröffentlichungs-Nr.

EP4799601

Anmeldetag

27. Februar 2025

Veröffentlichung

2. September 2026

Rechtsraum

EP

Abstract

The present invention relates to the field of medicinal tissue mineralisation, in particular, i.e. tooth remineralisation and bone regeneration with self-assembling peptides. Use of self-assembling peptides, such as P11-4, also designated Oligopeptide-104, in these processes leads to generation of hydroxyapatite, which is also present in natural enamel, dentin and bone. The inventors have discovered that this can be significantly accelerated by combining a self-assembling peptide (SAP) such as P11-4, calcium ions, phosphate ions, and a polymer in the form of particles encapsulating a cargo selected from at least one of the SAP, the calcium ions and the phosphate ions into a composition or kit. The invention also provides medical use of said composition or kit, in particular, in the tooth, for remineralisation of caries lesions, such as subsurface caries lesions, mineralisation of pits and fissures, treatment of sensitive teeth, pulp capping, and for bone regeneration.

Anmelder

Firma

vVardis AG

Land

🇨🇭 Schweiz