Herstellungsverfahren für Chromatographischen Träger

Details

Veröffentlichungs-Nr.

EP4825486

Anmeldetag

12. September 2024

Veröffentlichung

19. Juni 2025

Rechtsraum

EP

Abstract

To provide a method for easily producing a chromatographic carrier having a large dynamic binding capacity for an antibody or a fragment thereof, in which a proteinaceous ligand is less likely to leak during isolation, and aggregation between carriers is less likely to occur. A production method for a chromatographic carrier, including a ligand binding process, a ligand-bound carrier bed formation process, a ligand-bound carrier liquid-passing washing process, and a ligand-bound carrier stirring washing process. (Ligand binding process) a process of binding a proteinaceous ligand to the solid-phase carrier (Ligand-bound carrier bed formation process) a process of filling a ligand-bound carrier obtained in the ligand binding process into a container to form a ligand-bound carrier bed (Ligand-bound carrier liquid-passing washing process) a process of washing the ligand-bound carrier bed formed in the ligand-bound carrier bed formation process by passing a washing liquid therethrough one or more times (Ligand-bound carrier stirring washing process) a process of washing the ligand-bound carrier after the ligand-bound carrier liquid-passing washing process by stirring one or more times in a washing liquid

Anmelder

Firma

JSR Corporation

Land

🇯🇵 Japan