Spezifisch an humanes Herztroponin I bindendes DNA-Aptamer

Details

Veröffentlichungs-Nr.

EP2532748

Aktenzeichen

EP12151421

Anmeldetag

17. Januar 2012

Veröffentlichung

8. Oktober 2014

Erteilung

8. Oktober 2014

Rechtsraum

EP

IPC

C12N15/115G01N33/68

Abstract

Disclosed are a DNA aptamer specifically binding to human cardiac troponin I, and a composition and a diagnostic kit for the diagnosis of acute cardiovascular diseases, comprising the same. Being superior in specificity and stability to antibodies which are conventionally used to diagnose acute cardiovascular diseases, the DNA aptamers specifically binding to human cardiac troponin I can be developed into biosensors which determine human cardiac troponin I levels with high sensitivity and accuracy, greatly contributing to the diagnosis in an early stage of acute cardiovascular diseases. It is expected to lots of help for increase of diagnostic accuracy.

Anmelder

Firmen

Postech Academy-Industry Foundation
Postech Academy-industry Foundation

Land

🇰🇷 Südkorea

Fachgebiete