Detektion von Lcms-Komponenten mit Niedrigem Niveau durch Chromatographische Rekonstruktion

Details

Veröffentlichungs-Nr.

EP3355339

Aktenzeichen

EP18154157

Anmeldetag

30. Januar 2018

Veröffentlichung

3. September 2025

Erteilung

3. September 2025

Rechtsraum

EP

IPC

H01J49/00G01N30/72G01N30/86

Abstract

A method for analyzing a sample can include obtaining an exclusion list of retention time and mass-to-charge ranges corresponding to high abundance compounds within a sample; separating components of the sample using the chromatographic column; obtaining a first mass data set using the mass analyzer while excluding ions within retention time and mass-to-charge ranges of the exclusion list; generating an inclusion list of features of the first mass data set; fragmenting ions corresponding to features of the inclusion list; obtaining a second mass data set from the fragmented ions; and identifying and/or quantifying low abundance compounds based on the second mass data set.

Anmelder

Firma

Thermo Finnigan LLC

Land

🇺🇸 USA

Fachgebiete