Optimierung der Vierpoligen Kollisionszellen-Hf-Amplitude für Tandem-Massenspektrometrie

Details

Veröffentlichungs-Nr.

EP3370248

Aktenzeichen

EP18159569

Anmeldetag

1. März 2018

Veröffentlichung

2. Oktober 2019

Erteilung

2. Oktober 2019

Rechtsraum

EP

IPC

H01J49/00

Abstract

A mass spectrometer includes a collision cell and a system controller. The collision cell includes a plurality of rod pairs configured to generate pseudopotential well through the application of radio frequency potentials to the rod pairs. The collision cell configured to generate a target fragment from a parent ion by colliding the parent ion with one or more gas molecules. The system controller is configured to set a radio frequency amplitude of the radio frequency potentials to a default amplitude; monitor the production of a target fragment ion while adjusting the collision energy; set the collision energy to optimize the production of the target fragment ion; apply a linear full range ramp to the radio frequency amplitude to determine an optimal radio frequency amplitude; and set the radio frequency amplitude to the optimal radio frequency amplitude for the parent ion, target fragment ion pair.

Anmelder

Firma

Thermo Finnigan LLC

Land

🇺🇸 USA

Fachgebiete