Verfahren und Systeme zur Chromatografischen Ausrichtung

Details

Veröffentlichungs-Nr.

EP3690436

Aktenzeichen

EP20152609

Anmeldetag

20. Januar 2020

Veröffentlichung

10. Mai 2023

Erteilung

10. Mai 2023

Rechtsraum

EP

IPC

G01N30/86

Abstract

An exemplary chromatographic alignment system accesses a target file including data representative of a plurality of chromatographic features detected from a first sample and a reference file including data representative of a plurality of chromatographic features detected from a second sample. The system identifies, based on the target and reference files, a distinct retention time offset value for each chromatographic feature included in a first subset of the plurality of chromatographic features detected from the first sample. The system determines, based on the identified distinct retention time offset values for the chromatographic features included in the first subset and on a machine learning model, a distinct predicted retention time offset value for each chromatographic feature included in a second subset of the plurality of chromatographic features detected from the first sample. The system assigns the distinct predicted retention time offset value for each chromatographic feature included in the second subset.

Anmelder

Firma

Thermo Finnigan LLC

Land

🇺🇸 USA

Fachgebiete