Zusammensetzung für Temperatursensoren mit Graphenoxid, Dnazym und Pna und Verfahren zur Temperaturmessung damit

Details

Veröffentlichungs-Nr.

EP3792608

Aktenzeichen

EP20196273

Anmeldetag

15. September 2020

Veröffentlichung

1. September 2021

Erteilung

1. September 2021

Rechtsraum

EP

IPC

G01K3/04C12N15/11C12Q1/6816

Abstract

The present invention relates to a composition for temperature sensors including graphene oxide, DNAzyme and PNA and a temperature sensing method using the same. In the composition for temperature sensors, the temperature sensing method, and the kit for temperature sensors according to the present invention, when the DNAzyme/PNA duplex is dissociated at a certain temperature, graphene oxide adsorbs PNA with excellent selectivity and irreversibility, so it is enabled recall of temperature, which can permit delayed color development in the time of need. In addition, the target temperature can be easily and quickly detected with the naked eye through the color change of the colorimetric reagent, and the thermosensor is technically convenient and easy to apply, so it can be used in various biological applications. Moreover, it can be used as a barcode (on/off) system using a combination of PNA probes with various lengths, and thus can be broadly applied to sensing a diverse range of temperatures.

Anmelder

Firma

Korea Research Institute of Chemical Technology

Land

🇰🇷 Südkorea

Fachgebiete