Systeme und Verfahren zum Einfangen, Strecken und Nachweis von Polynukleotidsträngen

Details

Veröffentlichungs-Nr.

EP4721862

Anmeldetag

1. Oktober 2025

Veröffentlichung

8. April 2026

Rechtsraum

EP

IPC

B01L3/00, C12Q1/6806

Abstract

Systems and methods for trapping and detecting a polynucleotide strand in a channel. Methods may include labeling at least one subsequence within a polynucleotide strand to obtain a labeled polynucleotide strand having at least one label. Methods may additionally include providing a polymer to a surface of a channel and physically interacting the polymer with the surface of the channel. Methods may also include providing a sample including the labeled polynucleotide strand to the channel, applying an electric field to the labeled polynucleotide strand to promote a physical interaction between the labeled polynucleotide strand and the polymer at the surface of the channel to trap the labeled polynucleotide strand at the surface of the channel, and detecting the at least one label within the labeled polynucleotide strand.

Anmelder

Firmen

Robert Bosch GmbH
The Board of Trustees of the Leland Stanford Junior University

Land

🇩🇪 Deutschland