Enzymreinigung mit Chemisch Aktiviertem Kohlenstoff

Details

Veröffentlichungs-Nr.

EP4722226

Anmeldetag

6. Oktober 2025

Veröffentlichung

8. April 2026

Rechtsraum

EP

IPC

C07K1/14, C07K1/34, C12N9/00(SANOFI SA et al.)(SCARAB GENOMICS LLC et al.)(LEK PHARMACEUTICALS et al.)(SAVILLE BRADLEY A et al.)(UNIV JIANGNAN et al.)

Abstract

The present invention relates to the field of protein purification. The invention contemplates a method for purifying a fermentation-derived solution of a protein of interest comprising the following steps: contacting the fermentation-derived solution with chemically activated carbon in an amount ranging from 0.1 to 15 wt.-% of the solution; adjusting the pH to a value between 4 and 12, adjusting the temperature to a value between 2 °C to 60 °C; separating the chemically activated carbon from the solution; and thereby obtaining a clarified solution of the protein of interest. Moreover, it relates to a clarified solution of a protein of interest obtainable by or obtained by the method according to the invention and to the use of a chemically activated carbon for purifying a fermentation-derived solution of a protein of interest.

Anmelder

Firma

BASF SE

Land

🇩🇪 Deutschland