Altmann Stößel Dick Patentanwälte PartG mbB

The invention relates to an extraction system (110) for extraction of paramagnetic or diamagnetic particles (112) of different types from a fluid (114), the system (110) comprising: - at least one magnetic field generator (116) configured for generating a magnetic field having a magnetic field gradient along a z-axis; - at least one flow channel (120) configured for guiding the fluid (114) comprising the particles (112) into the magnetic field essentially along the z-axis, preferably in a manner that a magnetophoretic force induced by the magnetic field gradient acts on the at least one particle; wherein the extraction system (110) comprises at least one extraction unit (122) configured for extracting the particles (112) of different types from the fluid (114), wherein the at least one extraction unit (122) comprises at least one extractor coil (124) configured for generating at least one further magnetic field having a further magnetic field gradient, wherein the further magnetic field gradient has a component that is orthogonal to the z-axis. The invention further relates to a method for extraction of paramagnetic or diamagnetic particles (112) of different types from a fluid (114).

A micronutrient composition comprising several combinations of individual ingredients in forming Mix 11, G12, G13 and core mix formulation. The Core mix contains magnesium citrate, alpha-Ketoglutaric acid, L-Citrulline and Taurine. The Mix 11, G12 and G13 contains Magnesium Citrate, Alpha-Ketoglutaric Acid, Niacinamide, L-Glutamine, L-Citrulline, Sodium Pyruvate, Succinic acid, Vitamin B complex, Taurine, L-Cysteine, L-Methionine, L-Ascorbic Acid, Coenzyme Q10 or combination thereof. A method of administering and treating a specific disease which is due to one of an oxidative stress, impaired mitobiogenesis and ATP production in a mammal is disclosed.

The present invention relates to a polyol composition (PC) for the production of a polyurethane, in particular a thermoplastic polyurethane, comprising at least one compound (P1) having at least two hydrogen atoms which are reactive towards isocyanates and (P1) has the general formula (A1)-(B)-(A2). The invention furthermore relates to a process for producing a polyurethane, preferably a thermoplastic polyurethane, comprising mixing an isocyanate composition (IC) comprising at least one polyisocyanate (11); and a polyol composition (PC), comprising at least one compound (P1); and reacting the isocyanate composition (IC) and the polyol composition (PC) to form a polyurethane. The present invention also relates to the polyurethane obtained in the process as well as the use thereof for producing an article, in particular for producing an article selected from the group consisting of flooring, a shoe or a part of a shoe.

The present invention relates to a method for producing a display complex, the method comprising (I) providing a covalent mRNA-Puromycin Linker conjugate; (II) contacting the covalent mRNA-Puromcyin linker conjugate with an in vitro translation composition to produce a display complex comprising a polypeptide encoded by said mRNA, (III) optionally reverse transcribing said mRNA to a cDNA, and (IV) cyclisation of the polypeptide comprised in said display complex.

Es wird ein elektrisches Antriebssystem (116) zum Antreiben mindestens einer Tauchkreiselpumpe (114) vorgeschlagen. Das elektrische Antriebssystem (116) umfasst mindestens einen Reluktanz-Synchronmotor (117) oder mindestens einen Hybrid-Reluktanz-Synchronmotor (118), wobei mindestens einer der Motoren (117, 118) eine Rotorwelle (128), ein Lamellen (138) aufweisendes Rotorsegment (126) und einen Stator (134) umfasst, wobei das Verhältnis einer Länge (130) der Rotorwelle (128) zu einem Außendurchmesser (132) des Stators (134) ≥ 2 ist.Weiterhin werden ein Tauchkreiselpumpensystem 110 zur Fluidförderung und eine Verwendung mindestens eines Reluktanz-Synchronmotors (126) oder eines Hybrid-Reluktanz-Synchronmotors in einem Tauchkreiselpumpensystem (110) zur Fluidförderung vorgeschlagen.

The present invention relates to a method for assessing pancreatic cancer in a subject, said method comprising (a) determining the biomarkers Ceramide (d18:1;C24:0), Lysophosphatidylethanolamine (C18:0), Phosphatidylethanolamine (C18:0, C22:6), Sphingomyelin (d17:1; C16:0), and CA19.9 in a sample from said subject; (b) comparing the biomarkers determined in step (a) to at least one corresponding reference; and (c) assessing pancreatic cancer in said subject based on said comparing in step (b). The present invention further relates to a computer-implemented training method of training at least one trainable model for assessing pancreatic cancer, to an automated machine learning model, and to a system related thereto.

Es wird vorgeschlagen eine Reinigungsvorrichtung (110) zur Reinigung von Reinigungsgut (112). Die Reinigungsvorrichtung (110) umfasst mindestens eine Steuerung (114); mindestens eine Reinigungskammer (116) zur Aufnahme mindestens eines Reinigungskorbs (118); mindestens eine Beaufschlagungsvorrichtung (120) zum Beaufschlagen des in dem Reinigungskorb (118) angeordneten Reinigungsgut (112) mit mindestens einem Reinigungsfluid (122) in der Reinigungskammer (116); und mindestens eine Transportvorrichtung (124) zum automatischen Transport des mindestens einen Reinigungskorbs (118) von einem Einlauf (126) der Reinigungskammer (116) durch die Reinigungskammer (116) hindurch zu einem Auslauf (128) der Reinigungskammer (116). Die Transportvorrichtung (124) umfasst mindestens einen Korbmitnehmer (130) eingerichtet zur Ausführung einer Oszillationsbewegung umfassend eine Vorwärtsbewegung (132) in Richtung einer Transportrichtung (134) der Transportvorrichtung (124) bei der der Korbmitnehmer (130) den Reinigungskorb (118) in die Transportrichtung (124) vorantreibt und eine Rückwärtsbewegung (136) an dem Reinigungskorb (118) vorbei entgegen der Transportrichtung (134) der Transportvorrichtung (124); mindestens einen von der Steuerung (114) gesteuerten Antrieb (138) zum Antreiben der Oszillationsbewegung des mindestens einen Korbmitnehmers (130), umfassend einen Motor (140) und einen Frequenzumrichter (142), wobei die durch den Frequenzumrichter (142) bereitgestellte Antriebsfrequenz für den Motor (140) derart variiert, dass die Rückwärtsbewegung (136) des Korbmitnehmers (130) schneller ist als die Vorwärtsbewegung (132) des Korbmitnehmers (130).Weiterhin vorgeschlagen wird ein Verfahren zum automatischen Transport von mindestens einem Reinigungskorb (118) durch zumindest eine Reinigungsvorrichtung (110) sowie ein Computerprogramm zur Ausführung von zumindest einem Teil des Verfahrens und ein Computerlesbares Medium auf dem das Computerprogramm gespeichert ist

An organic electroluminescent device comprises a first electrode, a second electrode, and an organic layer disposed between the first electrode (104) and the second electrode (108), the organic layer (106) comprising at least one charge-neutral metal-organic coordination compound of general formula (1-1):with• M being Gd(III) or Ce(III),•independently representing each a singly electrically negatively charged ligand with• R₁ and R₃ being independently, preferably identical in each occurrence, selected from organyl groups having at least 6 atoms, and• R₂ and R₄ being independently, preferably identical in each occurrence, selected from the group consisting of hydrogen, deuterium, fluorine, nitrile, and an organyl group, and with• L representing a singly electrically negatively charged ligand, and• broken lines indicating coordinative and/or ionic bonds.

The present invention relates to optical coupling between optical components and, more particular, to an optical probe (1) configured for optical testing of at least one micro-optical component (50), to a method for producing an optical probe (1), and to a method for optical testing of at least one micro-optical component (50). The optical probe (1) is comprising:- a probe head (10), wherein the probe head (10) comprises a test component (2);- at least one micro-optical element (20), wherein the micro-optical element (20) is a separate element with regard to the test component (2) and in mechanical contact with the test component (2),wherein the micro-optical element (20) is configured to optically couple at least one light beam (3) between the test component (2) and the micro-optical component (50), thereby being configured to determine an emission characteristics of a coupling location (52) comprised by the micro-optical component (50) , wherein the micro-optical component (50) further comprises a beam-shaping element (51a), wherein the beam-shaping element (51a) is arranged in a manner that at least a portion of the light beam (3) is travelling through the beam-shaping element (51a).

An organic electroluminescent device comprises a first electrode, a second electrode, and an organic layer disposed between the first electrode and the second electrode, the organic layer comprising at least one charge-neutral metal-organic coordination compound, with the metal-organic coordination compound comprising at least one electrically negatively charged gallium compound of general formula (1-1): <img class="EMIRef" id="1da0d0c8-8e13-4782-87a6-f3dc7487ecae-ia01" /> with A, and B independently being substituted or non-substituted heterocyclic rings, and broken lines indicating e.g. a chemical bond or linking group at any available position.