Verfahren und System zur Durchführung von Zeitkorrelierten Einzelphotonenzählungsmessungen

Details

Veröffentlichungs-Nr.

EP4722696

Anmeldetag

7. Oktober 2024

Veröffentlichung

8. April 2026

Rechtsraum

EP

IPC

G01N21/64

Abstract

The disclosure pertains to a method of analyzing a time-correlated single photon counting measurement, the method comprising the steps of a) exciting the sample (10) by a plurality of successive excitation light pulses or any other form of periodically modulated light (11), b) detecting the radiation originating from the sample (10), thereby generating an electrical signal (12), out of which at least one detection event (13) is generated, each detection event (13) indicative of at least one photon originating from the sample (10) and having a measured relative time (t_p), c) providing extended information for at least one of said detection events (13), preferably for each of said detection events (13), the extended information being representative of at least one of the size and shape of the electrical pulse associated with the detection event (13) within the electrical signal (12), and d) generating a distribution of relative times reflecting one or more properties of the sample (10) based on said signal (12) and said extended information, wherein a corrected relative time tp′ is assigned to at least one detection event (13) which is based on the measured relative time (t_p) of the detection event (13) and on the extended information associated with the respective detection event (13) and/or a weight factor (w(t)) is assigned to at least one detection event (13) which is based on the measured relative time (t_p) of the detection event (13) and on the extended information associated with a plurality, in particular all, detection events (13) within a domain of interest (DOI).

Anmelder

Firmen

Prospective Instruments GmbH
Universität Zürich
Ost - Ostschweizer Fachhochschule

Land

🇨🇭 Schweiz