Differenzierungssteuerungsverfahren für Pluripotente Stammzellen

Details

Veröffentlichungs-Nr.

EP4733316

Anmeldetag

31. Januar 2018

Veröffentlichung

29. April 2026

Rechtsraum

EP

IPC

C07K14/78

Abstract

The present invention relates to a method for controlling differentiation of pluripotent stem cells, which method comprises selecting a laminin or a fragment thereof based on binding affinity for the pluripotent stem cells and inducing differentiation of the pluripotent stem cells in the presence of the laminin or a fragment thereof. Here, the binding affinity for cells can be assessed by time-course observation of the survival rate and motility of the cells. According to the present invention, a cell population containing any desired proportion of differentiated cells can be produced from pluripotent stem cells in a simple manner. The cell population obtained by this production method is very useful for cell therapy-based treatment strategies for diseases.

Anmelder

Firma

Osaka University

Land

🇯🇵 Japan

Fachgebiete