Erfassungsverfahren und Detektionsverfahren für Extrazelluläre Vesikel aus Krebszellen und Kit

Details

Veröffentlichungs-Nr.

EP4733762

Anmeldetag

21. Juni 2024

Veröffentlichung

26. Dezember 2024

Rechtsraum

EP

Abstract

A technology is disclosed for capturing or detecting extracellular vesicles derived from all cancers regardless of cancer type. A method of capturing cancer cell-derived extracellular vesicles contained in a biological sample includes a step of contacting the biological sample with (A) a polypeptide comprising IDI-ID2a domains of VAR2CSA protein derived from Plasmodium falciparum, (B) a polypeptide having 90% or more sequence identity with amino acid sequence of the polypeptide of (A) above, and binding to cancer cell-derived extracellular vesicles, or (C) a part of the polypeptide of (A) or (B) above, which is a polypeptide binding to cancer cell-derived extracellular vesicles, to bind the polypeptide and the cancer cell-derived extracellular vesicles.

Anmelder

Firmen

Toray Industries, Inc.
Kyoto University

Land

🇯🇵 Japan