Mewburn Ellis LLP

The disclosure relates to a method for manufacturing a foamed polymer product 1 having a series of openings 2 and compression mold 4 comprising a series of pins 5 for use in said method. The method comprising the steps of providing a foamed polymer preform 3 having a certain height, width and length and comprising a series of openings 2 extending into or through the preform 3; inserting the preform 3 into the compression mold 4 by sliding the preform 3 with the series of openings 2 onto the corresponding series of pins 5 of the compression mold 4; and shaping of the preform 3 in the compression mold 4 to form the product 1 having a compressed height, width and/or length by compressing the preform 3 inside the compression mold 4, in particular by pressing the top 6 and the base 7 towards each other and by heating of the preform 3 inside the compression mold 4.

An automated apparatus and system (100) for document processing and/or package labelling. The system comprises a base (102), a conveyor system (104), a scanner (120), a plurality of applicators (130), and a control system (140) contained in a housing mounted to the base. The control system communicates with an enterprise resource planning system server and is connected to the conveyor system, the sensors, and the applicators. The control system is configured to: receive from the scanner a package ID associated with a package on the conveyor system, determine from the ERP system server document and/or label specifications for the package in accordance with the package ID, and send control instructions to respective applicators in accordance with the determined document and/or label specifications. Each applicator is one of a print and apply label applicator, a document applicator or a document inserter, each configured to activate in response to receiving a respective control instruction from the control system.

The present disclosure relates to a pharmaceutical composition for preventing or treating sepsis comprising an odorant receptor Olfr164 modulator as an active ingredient, and by synthesizing a derivative that modulates the odorant receptor Olfr164 and confirming the activity of the derivative in cell lines stably expressing the target odorant receptor Olfr164 and in a sepsis animal model, the potential for use as a therapeutic agent for sepsis is demonstrated.

This present invention relates to the field of automated vending, particularly to a retail system and method. The retail system comprises a plurality of service robots (01), a plurality of storage units, and a scheduling unit. The storage units comprise station storage units (02) and mobile storage units (03). The station storage units (02) are arranged at predetermined locations, while the mobile storage units (03) are disposed inside the service robots (01). The scheduling unit is further configured to, in response to an order request from a user, select a target service robot from the plurality of service robots (01) based on the delivery location corresponding to the order request and the item to be delivered, and control the target service robot to deliver the item to the delivery location. The scheduling unit is also configured to instruct the service robot (01) to retrieve items from the station storage unit (02) and store them in the mobile storage unit (03) of the service robot (01). This system achieves a balanced optimization among product variety, lightweight inventory, and efficient delivery response under limited storage capacity, thereby enhancing the response speed and service quality of unmanned retail.

The present disclosure relates to a pharmaceutical composition for preventing or treating sepsis, including F177, which is an odorant receptor Olfr164 modulator, as an active ingredient. F177 was derived via establishment of a cell line that stably expresses a target odorant receptor Olfr164 and library screening in the cell line, and an activity of F177 was identified in a sepsis animal model, thereby ensuring an applicability as sepsis treatment.

There is provided an implementation technique that enables shuttling by reducing the circuit size in a quantum computer. One aspect of the present invention for solving the above problem is a quantum computer including: a quantum dot device having a plurality of gate electrodes; a basic signal generation source configured to generate a voltage to be applied to each of the plurality of gate electrodes; a rectangular wave generation unit configured to shape the voltage to be applied to each of the plurality of gate electrodes to have a rectangular waveform; and a filter function unit arranged between the rectangular wave generation unit and the plurality of gate electrodes to smooth the rectangular waveform.

Systems and methods described herein provide context-aware vulnerability prioritization using Software Bill of Materials (SBOM) data and real-time contextual information from IoT and OT devices. Upon validating SBOM data, the system gathers contextual data, including environmental and device-specific information, and verifies its integrity. The data is standardized and common vulnerability exposure data is used to match vulnerabilities in the SBOM. Severity metrics are applied and combined with contextual data to assess overall risk. Based on the risk, risk scores that indicate vulnerability severity are assigned and each risk is prioritized accordingly. The prioritized data is then categorized into levels, distinguishing between purely contextual, device-specific, or combined data. According to the level of prioritization, a real-time alert is provided for context-aware vulnerability management, enabling immediate threat response.

A printed circuit board (PCB) for an aerosol generating device is provided. The printed circuit board comprises: one or more power input terminals for receiving power from a power source, and one or more heater terminals for providing the power from the power input terminals to a heating system of the aerosol generating apparatus. A first outer layer of the printed circuit board comprises a plurality of signal traces and one or more copper pours. The first outer layer comprises: a first main zone comprising each of the one or more copper pours, and a first keep-out zone surrounding the one or more heater terminals, wherein the one of more copper pours are delineated by a perimeter between the first main zone and the first keep-out zone, and a shortest distance between the one or more heater terminals and the first main zone is at least 2mm.

An aerosol-generating device for use in an aerosol-generating system is provided. The aerosol-generating system comprising an aerosol-forming material and an aerosol-generating unit configured to generate an aerosol from the aerosol-forming material. The aerosol-generating device comprising: a puff sensor configured to detect a user puff; a power source configured to supply electrical energy to the aerosol-generating unit; and a controller communicatively coupled to the puff sensor to receive a signal indicative of the user puff from the puff sensor. The controller is configured to: determine a duration of the detected user puff based on the received signal; and increase an amount of electrical energy supplied to the aerosol-generating unit from the power source when the duration of the puff exceeds a predetermined threshold. There is also provided an aerosol-generating system, and a method of controlling operation of an aerosol-generating system

An aerosol-generating system is disclosed, the aerosol-generating system, comprising: a device body comprising: an internal chamber for receiving an article via an opening, the internal chamber being arranged within the device body; an aerosol-generating unit, the aerosol generating unit being configured to generate an aerosol from the article when the article is received in the internal chamber; a closure member arranged at the opening to control access to the internal chamber, wherein the closure member is moveable by a user between a closed position in which the closure member fully obstructs the opening of the internal chamber and prevents insertion of an article into the internal chamber, and an open position in which the closure member does not obstruct the opening of the internal chamber and an article may be inserted into the internal chamber; and a processing resource, wherein the processing resource is configured to detect a user input by means of user operation of the closure member and control a control function of the device body in response to the user input.