Rindermilchisolierte Pulverförmige Exosome, Nährstoffzusammensetzungen und Verfahren

Details

Veröffentlichungs-Nr.

EP4736670

Anmeldetag

5. November 2020

Veröffentlichung

6. Mai 2026

Rechtsraum

EP

Abstract

Bovine milk-isolated powdered exosomes comprise intact exosomes. Nutritional compositions comprise protein, carbohydrate, and/or fat, and exosomes isolated from bovine milk. A method of preparing powdered exosomes comprises centrifuging bovine milk to form a lipid fraction top layer, a whey fraction middle layer, and a first pellet of cells and debris, separating the whey fraction and centrifuging the separated whey fraction to remove additional fat, casein aggregates and debris and form a substantially clear whey fraction, microfiltering the substantially clear whey fraction to remove residual debris, centrifuging the microfiltered whey fraction to obtain a pellet containing exosomes, incubating the exosomecontaining pellet in aqueous medium to dissolve the pellet without disrupting exosome membranes to provide an exosome suspension, and drying the suspension to obtain the powdered exosomes. Methods of lowering a risk of developing, or treating, insulin resistance, prediabetes, or diabetes in a subject employ exosomes isolated from bovine milk.

Anmelder

Firma

ABBOTT LABORATORIES

Land

🇺🇸 USA