Abstimmbare Zellsubstrate

Details

Veröffentlichungs-Nr.

EP4752213

Anmeldetag

14. Dezember 2018

Veröffentlichung

3. Juni 2026

Rechtsraum

EP

IPC

C12N5/00

Abstract

This invention relates to a substrate for mammalian cell culture comprising a co-polymer hydrogel comprising monomeric units of acrylamide, bisacrylamide and a coupling compound, such as 6-acylamidohexanoic acid (6AHA). A cell adhesion molecule, such as a component of the extracellular matrix (ECM), is covalently coupled to the coupling compound monomeric units of the co-polymer. The stiffness and cell adhesion molecule density of the substrate can be independently controlled by altering the concentration of acrylamide and coupling compound in the hydrogel, respectively. Substrates and methods and kits for their production are provided, along with cell culture systems and methods of culturing mammalian cells.

Anmelder

Firma

Cambridge Enterprise Limited

Land

🇬🇧 Großbritannien