Klunker IP Patentanwälte PartG mbB

An integrated sheath assembly for inserting f a medical device such as a percutaneous pump into a vessel can include a first sheath having a first lumen defining a first opening between proximal and distal ends of the first sheath for passage of a portion of the pump and a second sheath having a second lumen defining a second opening between proximal and distal ends of the second sheath. The second lumen is expandable to allow passage of the first sheath containing the portion of the pump. The first sheath fills a space between the second sheath and the portion of the percutaneous pump when the first sheath containing the percutaneous pump is inserted into the second lumen. The first sheath has a first hub, and the second sheath has a second hub. In some embodiments, a single sheath and a movable connector can be integrated on the medical device.

This invention relates to an intravascular blood pump (1), comprising a pumping device (11) with a pump section (3) and a drive section (4), wherein the pump section (3) comprises a pump casing (2) having a primary blood flow inlet (211) and a primary blood flow outlet (22) hydraulically connected by a primary passage (30) and the drive section (4) comprises a stator (40) and a rotor (41) rotatable about an axis of rotation (10) and configured to rotate a primary impeller (31), the primary impeller (31) being configured to convey a primary blood flow from the primary blood flow inlet (211) to the primary blood flow outlet (22) along the primary passage (30), the drive section (49) further comprises an ancillary blood flow inlet (23) and an ancillary blood flow outlet (24) hydraulically connected by an ancillary passage extending through an axial gap (401) between the rotor (41) and the stator (40) and an ancillary impeller (42) arranged at a drive section end (DSE) of the rotor (41) and rotatable about the axis of rotation (10) along with the rotor, the ancillary impeller (42) comprising one or more ancillary impeller vanes (421) configured to convey an ancillary blood flow (ABF) from the ancillary blood flow inlet (23) to the ancillary blood flow outlet (24) along the ancillary passage in a direction toward a pump section end (PSE) of the pumping device (11), and the rotor (41) is mounted in a blood-purged radial sliding rotor bearing (47) with an inner rotor bearing surface (4211) and an outer rotor bearing surface (4311), and the ancillary impeller (42) forms the inner rotor bearing surface (4211) of the radial sliding rotor bearing (47).

A crimp tool facilitates crimping a resiliently radially compressible human-implantable catheter pump, and transferring the crimped pump into a tubular transfer sheath, by pulling the heart pump through an elongated tube that defines a tapered longitudinal bore. The bore has an inside dimension that tapers gradually along the length of the bore. A large end of the bore is sufficient to accept an uncrimped heart pump. A small end of the bore has a dimension similar to an inside dimension of the transfer sheath. A proximal end of the tube has a hub. A proximal end of a bore through the hub is configured to receive a distal end portion of the transfer sheath coaxially with the tube bore. Optionally, a latch is configured to releasably restrain the distal end portion of the transfer sheath within the hub.

An introducer set (1) for providing vascular access in a patient's body comprises an Introducer sheath (10) and a dilator (20). The introducer sheath (10) has a tubular body (11) made of flexible material with a distal portion (12), a proximal portion (13) and an inner surface, the proximal portion (13) being configured to be inserted into a patient's vessel to allow a medical device (100) to be inserted through the introducer sheath (10) into the patient's vessel. The tubular body (11) of the introducer sheath has a wall thickness (d) of 0.3 mm or less. The dilator (20) has a body (21) with a proximal portion (23), a distal portion (22) and an outer surface, the dilator (20) being insertable into the introducer sheath (10) such that its proximal portion (23) extends proximally of the introducer sheath (10) when the dilator (20) is inserted in the introducer sheath (10). At least one of the dilator (20) and the introducer sheath (10) comprises a stiffening structure (25) imparting stiffness to the tubular body (11) of the introducer sheath (10), wherein said stiffening structure (25) can be released, removed or otherwise deactivated.

Eine einfach verriegelbare Schnellkupplung (10) zum lösbaren Verbinden eines Schlauchs (12) mit einem implantierbaren Apparat weist ein mit dem Schlauch (12) verbindbares, erstes Ansatzstück (14) und ein mit dem Apparat verbindbares zweites Ansatzstück (16) auf, wobei die Ansatzstücke (14, 16) im verriegelten Zustand gegeneinander verdrehbar sind.

An intravascular blood pump (200) includes a pump housing (211) having an input port (214) and an output port (216). A relatively short intake cannula (226) may draw blood in through an intake port (230) and deliver the blood to the input port (214) of the pump housing (211). The intake cannula (226) is relatively short, to prevent excess hydraulic loss. An outflow hose (234) is connected to the output port (216) of the pump housing (211), so as to convey blood exiting the output port (216) through the outflow hose (234) in a downstream direction to a discharge port (238), e.g. into an aorta or other blood vessel (205). Despite the short intake cannula (226), the outflow hose (234) longitudinally separates the intake port (230) from the discharge port (238) sufficiently so the intake port (230) and the discharge port (238) remain on opposite sides of a heart valve, despite inadvertent longitudinal shifts of the intravascular heart pump (200).

A blood pump (1) for supporting a patient's heart comprises a flow cannula (4) having a distal end (10) and a proximal end (11) opposite the distal end (10), wherein the distal end (10) of the flow cannula (4) is configured to be connected to the patient's heart or a blood vessel in order to establish a fluid communication between the blood pump (1) and the patient's heart and blood vessel, respectively. The flow cannula (4) comprises a distal portion (5) having said distal end (10) and a proximal portion (6) having said proximal end (11). The flow cannula (4) further comprises an intermediate portion (7) attached to the distal portion (5) and the proximal portion (6), wherein the intermediate portion (7) allows twisting thereof with a lower force than the distal portion (5) and the proximal portion (6). The intermediate portion (7) is configured to be fully occluded by twisting it. At least a portion of the intermediate portion (7) either alone or in combination with the distal portion (5) is adapted to be permanently attached to the patient's heart or a blood vessel.

A furnace tube and a using method of the same are provided. The furnace tube comprises a chamber for processing a wafer; a normal-pressure gas intake device and a low-pressure gas intake device configured to supply gas to the chamber, wherein each of the normal-pressure gas intake device and the low-pressure gas intake device is independently connected to the chamber; a normal-pressure control device and a low-pressure control device configured to control an air pressure in the chamber, wherein each of the normal-pressure control device and the low-pressure control device is configured to independently control the air pressure in the chamber; and a normal-pressure gas injection pipe located inside the chamber and connected to the normal-pressure gas intake device, and a low-pressure gas injection pipe located inside the chamber and connected to the low-pressure gas intake device. The present disclosure achieves compatibility of normal-pressure and low-pressure process treatment through one furnace tube.

A sheath (10) for producing a fully sealed access to the interior of a vessel of an animal or human body comprises a base sheath (20) having a tubular body defining a pass-through channel (22). The base sheath (20) is adapted to be inserted into the vessel through a vessel aperture. The sheath further comprises an expansion device (26) which is adapted to cooperate with the base sheath (20) such that the outer diameter (d; D) of the sheath (10) increases in the region of the vessel aperture with the sheath (10) in a stationary position in the vessel and upon actuation of the expansion device (26).

Time-series data formed by acquiring values indicating amounts or states of a plurality of biological materials for each biological material at a plurality of time points is prepared, the plurality of biological materials are divided into a plurality of groups on the basis of temporal variations of time-series data of the respective biological materials, representative time-series data indicating a state of each group is generated on the basis of time-series data of at least one biological material included in each group, and dependencies between the groups are estimated on the basis of the representative time-series data of each group.