Analoge Ereignisdetektionsschaltung für eine Nanoporenanordnung

Details

Veröffentlichungs-Nr.

EP4575493

Aktenzeichen

EP23217434

Anmeldetag

18. Dezember 2023

Veröffentlichung

25. Juni 2025

Rechtsraum

EP

IPC

G01N33/487

Abstract

This disclosure relates to nanopores and nanopore arrays. A readout device for a nanopore array is provided, and an analog detection circuit for the readout device. The detection circuit is connectable to a readout electrode of the nanopore array and, in a detection mode, applies a bias voltage to the readout electrode. Further, it extracts a baseline current from an input current flowing through the readout electrode when the bias voltage is applied, and outputs a digital signal indicating that a current event occurred, if the input current changes by a predetermined threshold value compared to the baseline current. The readout device comprises the detection circuit and a logic device. The logic device determines, based on the digital signal received from the detection circuit, whether a translocation event occurred in the nanopore. In this case, it provides an instruction signal to the detection circuit, to switch from the detection mode to a readout mode

Anmelder

Firmen

Imec VZW
Katholieke Universiteit Leuven

Land

🇧🇪 Belgien

Fachgebiete