Morabito, Sara

Devices, systems, instruments, and methods for promoting healing and stability for bone fractures. The bone stabilization system may include a periprosthetic plate configured to treat a periprosthetic fracture around an existing prosthesis. The periprosthetic plate may be especially suitable for the fixation of fractures and fragments in the greater trochanter region of the proximal femur. The periprosthetic plating may be used to create a rigid construct with permanent fixation to promote primary healing and stability.

Smart surgical instruments, systems, and methods for correcting a spinal deformity. The smart instruments are configured to sense and measure data, for example, related to screw insertion torque, segmental and global spine stiffness, correction force, rod reduction force, spinal alignment, or other metrics, which provide objective intraoperative data to the surgeon in real time. This data helps ensure that each action taken during the surgery is as precise as possible, minimizing risks and improving the effectiveness of the intervention.

A module (1, 1', 1", 1"') for a partition wall (27), comprising:- a first frame (2) comprising elements that are integrally associated with each other to form a border delimiting a first opening (5);- a second frame (6) comprising elements that are integrally associated with each other to form a border delimiting a second opening (7);- a first plate-like body (8, 8'), integrally associated in a perimetric portion thereof with the first frame (2);- a second plate-like body (9, 9'), integrally associated in a perimetric portion thereof with the second frame (6);- two opposite and parallel posts (10), which are detachably associated with the first frame (2) and the second frame (6), by way of engagement means (11), at the first lateral elements (2c) of the first frame (2) and at the second lateral elements (6c) of the second frame (6);- at least one transverse profiled element (12), at least partially interposed between the posts (10);the engagement means (11) comprise one or more contoured plates (13), which are integrally associated with the first frame (2) and with the second frame (6);the contoured plates (13) are selectively engaged in slots (15), which are provided in the posts (10).

A box (1) for fan coil units, which comprises a box-like body (7), arranged vertically when installed, with a substantially parallelepiped shape that defines a removable bottom (8), two longitudinal side walls (9a, 9b) and a top (10), all connected to a flat base (11), and a cover (12);the removable bottom (8) comprises a first breakable zone (18) and a housing (19), fitted with a condensate drain, for a removable trap (21) that cooperates with guide means (24a, 24b) associated proximate to the flat base (11) proximate to the opening (15);the top (10), the longitudinal side walls (9a, 9b) and the flat base (11) have, respectively, second, third and fourth breakable zones (27, 28, 29);the first, the second and the third breakable zones 18, 27, 28 are adapted to accommodate at least delivery (4) and return (5) conduits for refrigerated water or water at high temperatures.

Custom patient-specific interbody implants, systems, and methods of generating custom implants. The implants may include upper and lower surfaces with an irregular surface topography, which are custom contoured to match the adjacent vertebral endplates of a specific patient. The method may include uploading images of the spine for the patient and processing the images into a virtual three-dimensional model of the spine including topography of individual vertebral bodies. The user may automatically and/or manually manipulate the virtual three-dimensional model to pre-operatively simulate a desired correction to the spine. The virtual implant model may be generated based on the desired correction and the topography of adjacent vertebral bodies.

Functional alignment of a 3D image of pelvis includes identifying a reference points on each 2D image of weight-bearing pelvis; identifying corresponding reference points on a 3D image of pelvis in a non-weight bearing position; constructing references on the 2D images based on the reference points on each respective image, constructing a corresponding reference on the 3D image based on the reference points thereon; and aligning the corresponding references of the 3D image with the references of 2D images, to provide a functionally aligned 3D image to more accurately plan placement of an acetabular shell. Another aspect of the invention determines an acetabular center of rotation (CoR) calculations for use in navigation during a THA surgery, including obtaining a point cloud of a surface of an acetabulum with a navigated instrument during the THA surgery; creating an acquired surface of the acetabulum based on the point cloud; extracting an acetabular CoR from the acquired surface for use in alignment and registration.

An independent, surgical screw placement system makes use of an aiming jig. The aiming jig has components and features which can be suitably adjusted so that an independent or extra-plate screw avoids crossing the nominal trajectories of other joint screws securing a surgical plate to a foot in an associated surgery. The aiming jig has a telescoping arm which can be adjusted to a variety of potential trajectories for the independent surgical screw until a desired trajectory for such independent screw has been determined.

Disclosed are a vaginal foam formulation and a preparation method therefor, which belong to the technical field of pharmaceuticals. Provided is a vaginal foam formulation with estradiol as an active ingredient. In the present disclosure, estradiol is prepared as a vaginal foam formulation, which exhibits good compliance, has a large contact area within the vagina, and allows for rapid release of estradiol. Therefore, the vaginal foam formulation has strong targeting and quick onset of action for diseases caused by estrogen deficiency, and features accurate administration dosage and convenient use.

Aspects include a surgical robot for use in a total hip arthroplasty (THA) procedure, and related methods. In some cases, the surgical robot includes: a robot arm for holding a surgical instrument; and a controller coupled with the robot arm, the controller programmed to: detect a position of the surgical instrument in at least one attraction volume corresponding with a planned trajectory of the surgical instrument for the THA procedure, the at least one attraction volume defined in part by a point and an axis extending from the point; and while the surgical instrument is in the at least one attraction volume during the THA procedure, provide assistance to movement of the surgical instrument in a direction toward the at least one attraction volume.

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