Terumo Patente

Provided is a means configured to further improve antithrombogenicity in a medical device. A medical device of the present invention is a medical device including: a base material; an antithrombogenic layer including a polymer fixed to the base material, in which the polymer includes: a structural unit a derived from a first monomer bonded to the base material and including a reactive group that reacts with a hydroxyl group or a carboxyl group and an ethylenically unsaturated group; a structural unit B including a polymer chain including a structural unit b derived from a first antithrombogenic monomer including a carboxyl group and an ethylenically unsaturated group, and including a terminal of the polymer chain bonded to the structural unit a; and a structural unit C derived from a copolymer including a structural unit c1 derived from a second monomer including an amino group and bonded to the structural unit b and a structural unit c2 derived from a second antithrombogenic monomer.

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Provided are: a penetration catheter that can effectively support a device to be inserted inside and can improve operability of the supported device while having high penetrability into a lesion of a vein; a treatment method; a guide wire; and a catheter system. A penetration catheter 40 used for penetrating a lesion of a vein includes a second tube body 41 that has an outer diameter constant portion 45 having a constant outer diameter in a major axis direction, an outer tapered portion 46 having an outer diameter tapered from a distal end of the outer diameter constant portion 45 in a distal end direction, an inner diameter constant portion 47 having a constant inner diameter in the major axis direction, and an inner tapered portion 48 having an inner diameter tapered from a distal end of the inner diameter constant portion 47 in the distal end direction, in which an outer diameter of the outer diameter constant portion 45 is 2.7 ± 0.1 mm, an inner diameter of the inner diameter constant portion 47 is 1.6 ± 0.1 mm, an outer diameter of a most distal end of the tube body is 1.7 ± 0.1 mm, and an inner diameter of a most distal end of the second tube body 41 is 1.45 ± 0.1 mm.

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A collection kit (10) includes an inflow tube (12) to which a medical bag (80) is connected, and a collection bag (14) connected a downstream of the inflow tube. The collection bag includes a plurality of housing chambers (28), a common flow path (24) connected to the downstream of the inflow tube, and a plurality of coupling flow paths (26) branching from the common flow path and respectively communicating with the plurality of housing chambers. A collection target (M) housed in the medical bag is temporarily stored in the plurality of housing chambers. The collection target is transferred from the plurality of housing chambers to the plurality of sampling containers (90), respectively.

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A filter device (10) according to the present invention is to be mounted on a centrifugal separator (50) and includes: a first space (18) into which blood flows; a second space (20) from which the blood flows out; a partition wall (22) separating the first space and the second space; a communication port (28) establishing communication between the first space and the second space; and a white-blood-cell removal filter (24) disposed in the second space. The second space is located between the first space and a rotation center (LA) of the centrifugal separator.

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An object of the present invention is to provide means capable of imparting excellent functionality (for example, antithrombogenicity) in a medical device (particularly, a medical device including a metal base material). The object is achieved with a medical device including: a metal base material; and a functional layer having a polymer including a constituent unit A derived from a bonding monomer having a phosphoric acid group or a phosphonic acid group and an ethylenically unsaturated group, which is bonded to the base material, and a functional polymer chain formed of a constituent unit B derived from a functional monomer, with a terminal of the functional polymer chain being bonded to the constituent unit A.

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A filter device (10) according to the present invention is to be mounted on a centrifugal separator (50) and includes: a first space (18) into which blood flows; a second space (20) from which the blood flows out; a partition wall (22) separating the first space and the second space; a communication port (28) establishing communication between the first space and the second space; and a white-blood-cell removal filter (24) disposed in the second space. The first space and the second space are arranged in a first direction (D1) intersecting a centrifugal direction (DC), and the inlet port (14a) and the communication port are located between a center line (C12) along the first direction and a rotation center (LA) of the centrifugal separator.

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