Terumo Patente

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Provided is a medical sheet that increases rigidity of a main body portion constituting the medical sheet and prevents or suppresses twisting when disposed in a biological organ.The medical sheet includes a sheet-shaped main body portion 10 containing fibers made of a biodegradable material, and the main body portion is formed with a plurality of through-holes 11 and includes a fused portion 50 in which the fibers are gathered and fused around the through-holes.

A balloon according to the present disclosure is a balloon that can be inserted into a living body, the balloon including an expansion portion that defines a central axis extending along an insertion direction from a proximal side to a distal side, the expansion portion including a transmissive layer capable of transmitting light emitted inside to an outside, and a light shielding layer that covers the transmissive layer and has a transmittance of the light lower than that of the transmissive layer, the expansion portion including a window region in which the transmissive layer is not covered with the light shielding layer and a light shielding region in which the transmissive layer is covered with the light shielding layer, and the window region of the expansion portion in an expanded state including a first window portion, and a second window portion arranged spaced apart from the first window portion on the proximal side with respect to the first window portion and more inclined with respect to the central axis than the first window portion.

[Object] Provided is a living body indwelling object capable of effectively suppressing the onset of inflammation derived from a porous structure made of a biodegradable polymer while preventing scattering of a plaque and a thrombus at the time of stent expansion. [Solving Means] A living body indwelling object 100 includes an expandable tubular stent 10 and a porous structure 20 made of a first biodegradable polymer, the porous structure being disposed to cover the stent, in which the stent includes a drug carrying portion 18 containing a second biodegradable polymer and a drug, and a decomposition time of the porous structure is substantially the same as a decomposition time of the drug carrying portion or shorter than a decomposition time of the drug carrying portion.

The present invention provides a method for manufacturing an expansion body, a method for manufacturing an expansion body assembly, and a medical device, with which it is possible to inhibit breakage of an expansion body during manufacture.Provided is a method for manufacturing an expansion body (21) that includes a plurality of struts (50) extending along the axial direction and aligned in the circumferential direction around the axial direction, and has, in the middle in the axial direction, a waist portion (55) having a reduced outer diameter, the method including expanding an inside of a base material (180) having a tubular shape and including the plurality of struts (50) using an inner mold, and restricting an outside of the base material (180) with an outer mold (150) in order to form a bottom (56) having the smallest outer diameter of the waist portion (55) and an upright portion extending radially outward from the bottom (56).

Provided is a medical device capable of preventing an excessive clearance from being formed with an inner wall of a delivery device when a puncture device is delivered to a target site in a living body, and capable of easily and smoothly performing protrusion of the puncture device from a first lumen of an outer sheath and accommodation of the puncture device into the first lumen of the outer sheath by operating forward and backward movement of a hand handle portion. A medical device 10 is configured to be retractably inserted into a channel 511 of an insertion portion 510 of an endoscope device 500, and includes a puncture device 100, an outer sheath 200 into which the puncture device is inserted, and a hand handle portion 300 disposed on a proximal end side of the puncture device and the outer sheath. The hand handle portion includes a first connection portion 320 connected to the outer sheath, and a second connection portion 330 connected to at least a part of the puncture device and relatively moving forward and backward with respect to the first connection portion to cause a distal end of the puncture device to protrude from a distal end of the outer sheath.

To suppress stagnation portion of blood flowing between a housing (10) and a hollow fiber membrane layer (30) and improve antithrombogenicity, an oxygenator (100) includes a housing (10) having a cylindrical shape and including a blood inflow port (14) and a blood outflow port (15), and a hollow fiber membrane layer (30) formed by winding a hollow fiber membrane and accommodated in a housing (10), the oxygenator in which blood flowing in from the blood inflow port (14) flows from one end toward the other end in a longitudinal direction of the housing (10) and flows out from the blood outflow port (15), in which the housing (10) includes a plurality of raised portions (16) (inner raised portions 16b) raised radially inward from an outer surface of an annular inner peripheral portion toward a surface of an innermost layer of the hollow fiber membrane layer (30) and extending from a distal end toward a proximal end of the housing (10), and a recess (17) adjacent to a downstream end of the raised portion (16) in a blood circulation direction, and formed continuously in a circumferential direction of the inner peripheral portion so as to face an outflow portion of the blood in a blood flow path (50) communicating with the blood outflow port (15).

To suppress stagnation portion of blood flowing between a housing (10) and a hollow fiber membrane layer (30) and improve antithrombogenicity, an oxygenator (100) includes a housing (10) having a cylindrical shape and including a blood inflow port (14) and a blood outflow port (15), and a hollow fiber membrane layer (30) having a stacked structure obtained by winding hollow fiber membranes (31) accommodated in the housing (10), the oxygenator in which blood flowing in from the blood inflow port (12) flows from one end toward the other end in a longitudinal direction of the housing (10) and flows out from the blood outflow port, in which, in the hollow fiber membrane layer (30), a winding interval (P1) of the hollow fiber membranes wound in an outermost layer in the stacked structure is wider than a winding interval (P2) of the hollow fiber membranes in other layers.

To suppress stagnation portion of blood flowing between a housing (10) and a hollow fiber membrane layer (30) and improve antithrombogenicity, an oxygenator (100) includes a housing (10) having a cylindrical shape and including a blood inflow port (14) and a blood outflow port (15), and a hollow fiber membrane layer (30) formed by winding a hollow fiber membrane and accommodated in a housing (10), the oxygenator in which blood flowing in from the blood inflow port (14) flows from one end toward the other end in a longitudinal direction of the housing (10) and flows out from the blood outflow port (15), in which the housing (10) includes a plurality of raised portions (16) raised radially inward from an inner peripheral surface of the housing (10) and extending from a distal end toward a proximal end of the housing (10).