Brand Murray Fuller LLP

An oral adhering lozenge including a sparsely water-soluble active ingredient is provided. In one aspect, an oral adhering lozenge having at least 5 milliequivalents (mEq) of acid neutralizing capacity is provided. The acid neutralization capacity may be achieved with at least 200 milligrams of a sparsely water-soluble antacid, such as calcium carbonate. To achieve a fast enough speed of dissolution with such a large quantity of sparsely water-soluble active ingredient, one or more water-soluble ingredients acting as a compression binder and/or bulking agent that dissolves quickly in water is included in an amount equal to greater than the sparsely soluble active ingredient in the non-adhesive layer.

A system can include one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, cause the one or more processors to perform operations. The operations can include receiving a service request for a vehicle. The operations further can include analyzing the vehicle. Analyzing the vehicle can include comparing the type of the vehicle and the condition of the vehicle to historical data to generate comparison information. The operations also can include generating a sourcing plan. Generating the sourcing plan can include identifying one or more vehicle parts used for the service request based at least on the comparison information and an automated sourcing function to source the one or more vehicle parts used for the service request. The operations further can include facilitating an order to obtain the one or more vehicle parts. Other embodiments are disclosed.

A thermal diffusion unit (120, 200) is fluidly connected to a combustion engine (100) via a flue line (130, 132). The thermal diffusion unit (120, 200) has a plurality of plates (212, 214) assembled in a parallel configuration, including a pair of heating plates (212) having a heating fluid gap (226) extending therebetween and a pair of cooling plates (214) having a cooling fluid gap (236) extending therebetween. A diffusion sheet (240) is positioned between the pair of heating plates (212) and the pair of cooling plates (214), such that the diffusion sheet (240) interfaces on a first side with one of the heating plates (212) and interfaces on an opposite side with one of the cooling plates (214). The diffusion sheet (240) includes a plurality of interconnected thermal diffusion cells (310) arranged in a repeating pattern.

De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.

A swim block for allowing a user to jump or dive into a swimming pool or other body of water from a vertical distance higher than the swimming pool, the swim block adapted to allow a user to jump or dive off the swim block with more force and distance when entering the pool, comprising: a base adapted for positioning on a surface near or adjacent to a portion of a perimeter area of the swimming pool, the base having an upper end; and a swim platform having a bottom surface in contact with the upper end of the base such that the swim platform is positioned at a vertical distance higher than the swimming pool, the swim platform having an upper surface and a front portion, the front portion of the swim platform having curved or rounded shape and terminates into the upper surface; wherein the base extends downward from the bottom surface of the swim platform and positions the swim platform above the swimming pool at the portion of the perimeter area of the swimming pool.

Provided herein are compositions, devices, systems and methods for generation and use of biomolecule-based information for storage. Further provided are devices comprising addressable electrodes controlling polynucleotide synthesis (deprotection, extension, or cleavage, etc.) The compositions, devices, systems and methods described herein provide improved storage, density, and retrieval of biomolecule-based information.

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