Sugrañes, S.L.P

Computer implemented method for selecting emotional stimuli control (X) among emotional stimuli candidates (V,S,N) for a group of individuals to be used in signal denoising to isolate the true cerebral signal, wherein the method comprises the following sequence of steps: determining fNIRS related superficial signals (LS,RS) and neural signals (NS) for each of the individual of the group subject to emotional stimuli candidates; calculating a superficial signal group response (SGR) and a neural signal group response (NGR) for each emotional stimuli candidate, and the significance (A,B) of each group responses; and selecting as an emotional stimuli control (X) for the group an emotional stimuli that does have a significance (A) superficial signal group response (SGR), and has a no-significance (B) corresponding neural signal group response (NGR). Also a data processing apparatus, a computer program and a computer-readable storage medium, related to the computer implemented method are disclosed.

The present invention relates to a retention device for container vial (1), comprising a clamping jaw (2) configured to surround and retain the container vial (1), wherein the clamping jaw (2) is coupled to a side push button (3) acting against elastic push means (4), such that when said side push button (3) is pressed, a space (6) is opened for inserting the container vial (1), and when said side push button (3) is released, said space (6) is closed so that the container vial (1) is retained, thereby enabling the container vial (1) to be stably retained in a preferably vertical orientation, facilitating the placement of labels on vials in a vertical manner for automated manufacturing processes.

The present invention relates to a method of preparing an in vitro or ex vivo cell culture or a cellular model of atopic dermatitis or of pityriasis alba comprising a step of exposing a population of cells comprising keratinocytes and melanocytes to a culture medium, the culture medium comprising cytokines selected from the group consisting of IL-4, IL-13, IL-31 and combinations thereof. The present invention also relates to a cell culture obtained by such method, wherein the cell culture comprises keratinocytes, melanocytes and cytokines selected from the group consisting of IL-4, IL-13, IL-31 and combinations thereof. The present invention also relates to a cellular model of atopic dermatitis or of pityriasis alba obtained by such method, wherein the cellular model comprises keratinocytes and melanocytes. The present invention also relates to the use of such cell culture or of such cellular model for studying in vitro or ex vivo pigmentation/depigmentation mechanisms and modulators of these mechanisms and for screening in vitro or ex vivo pharmaceutically or cosmetically active molecules suitable for preventing, treating or attenuating a skin disorder or conditioning a skin in a subject in need thereof.

The present disclosure relates to a cosmetic composition for rejuvenating the skin comprising between 0,01% and 0,5% by weight with respect to the total weight of the composition of a precursor of retinoic acid selected from the group consisting of retinaldehyde, retinol, retinyl retinoate, retinyl esters and combinations thereof, between 0,0001% and 0,01% by weight with respect to the total weight of the composition of an anti-aging or antioxidant peptide, and between 0,0000005% and 0,000005% by weight with respect to the total weight of the composition of a growth factor, wherein the precursor of retinoic acid is encapsulated by an encapsulating agent comprising phospholipids. The present disclosure also relates to a method for rejuvenating the skin, comprising the topical application of the cosmetic composition disclosed herein and to a use of the cosmetic composition disclosed herein for rejuvenating the skin, by means of its topical application.

Covering system for covering a base surface overflow channel embedded in a base surface with a covering system, wherein the covering system comprises a cover (10) with a first through hole (11); and a frame including a hinge configuration (24) adapted to cooperate with the cover (10) to pivotably drive the cover (10) around a hinge axis (HA) between a closed position, and an open position, wherein the frame is made of several independent frame elements (21a, 21b, 22a, 22b), each frame element (21a, 21b, 22a, 22b) including at least one attachment configuration (23), and wherein the hinge configuration (24) is included in two opposed frame elements; and the hinge configuration (24) of the frame cooperates with the first through hole (11) of the cover (10) determining the alignment of the hinge axis (HA) with the first through hole (11) of the cover (10).

The present invention relates to an instrument (100) which comprises an embedding and guiding portion (1), a covering portion (2) forming a surface, and an intermediate joining portion (3) between the other two portions with which it is made in a single piece. The intermediate joining portion has a greater flexibility than the rest of the piece and can be easily folded by manually applying some force against the covering portion in the direction of the embedding and guiding portion when the latter is embedded. The instrument can move from a non-operative position to an operative covering position in which the covering portion is above the embedding and guiding portion, covering as a kind of visor an outlet edge (12) and part of the space adjacent thereto extending in an opposite direction to the embedding, completely covering and protecting the entire mouth of a collection container.

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The present invention relates to a platform door (1) for accessing train doors (2) from a platform (3) comprising a plurality of sliding mobile panels (5) that can slide laterally in an independent manner by means of respective tractions means (6), wherein each mobile panel (5) has a fixed panel length (11) and is designed to slide laterally and be arranged adjacent to other mobile panels (5) adopting a closing position (A) leaving no passageway (7) between mobile panels (5), and each mobile panel (5) being further designed to slide laterally and at least partially overlap with one of the adjacent mobile panels (5) thereof, adopting an opening position (B) defining passageways (7) between mobile panels (5) for accessing train doors (2).

Zusammenfassung wird geladen …

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