Beckman Coulter, Inc. Patente

A first aspect of the present disclosure is related to a transport system, comprising:- a first linear transport element, configured to transport carriers along a linear path,- a turntable, configured to transport carriers along a circular path,wherein the turntable comprises a rotatable disc comprising a plurality of recesses, each configured to hold a single carrier,wherein the first linear transport element and the turntable are positioned adjacent to each other to enable a transfer of a first carrier, the first carrier being transported on the first linear transport element, from the first linear transport element to a first recess of the rotatable disc,- a guiding element, configured to constrain an angular displacement of the first carrier about a longitudinal axis of the first carrier when the first carrier is transferred from the first linear transport element into the first recess of the rotatable disc.

A first aspect of the present disclosure is related to a turntable for moving biological samples,configured to:- receive a plurality of carriers from at least a first transportation element;- move the plurality of carriers to at least a second transportation element;- relieve the plurality of carriers individually to at least the second transportation element;wherein the movement from the first transportation element to at least the second transportation element is performed by a rotating means of the turntable.

A robotic transport system includes a robotic gripper that moves in at least one of a first axis, a second axis, and a third axis to be adjacent to a first instrument. The first axis, the second axis, and the third axis are mutually perpendicular with respect to one another. The system controls the robotic gripper to pick up labware from the first instrument, moves the robotic gripper in at least one of the first axis, the second axis, and the third axis to be adjacent to a second instrument, adjusts the robotic gripper to change from a first profile to a second profile, and controls the robotic gripper to position the labware in the second instrument.

The present disclosure provides a method (400) of evaluating a fluidic substance (10) having particles (11). The method (400) comprises capturing a reference image (202) of at least a portion of a container (102) that is in an empty state; determining a reference grayscale value (V1) of at least a portion of the reference image (202); aspirating a volume of the fluidic substance (10) into the container (102); capturing a test image (252) of the container (102) containing the aspirated volume of the fluidic substance (10); determining a test grayscale value (V2) of at least a portion of the test image (252); calibrating a universal calibration curve (56) relating particle concentration and grayscale value based on the reference and test grayscale values (V1, V2); and determining a particle concentration (P1) in the fluidic substance (10) based on the test grayscale value (V2) and the calibrated universal calibration curve (60).

The present invention relates to a method for causing the preparation of a set of Quality Control, QC, sample containers, wherein each QC sample container comprises a QC material for controlling the quality of at least a clinical test of a laboratory analyzer. The method comprises: obtaining, by a computing device, QC data comprising information specifying a set of QC sample containers to be prepared and, for each QC sample container of the set of QC sample containers, a respective volume of the QC material to be included in said each QC sample container; and causing at least a portion of a primary volume of QC material included in a primary QC sample container to be aliquoted, based on the QC data, into the QC sample containers of the set of QC sample containers.

The present invention relates to a method, comprising:obtaining, by a computing device, a plurality of tests to be performed by an Automated Laboratory System (ALS) on a biological sample,determining, by the computing device among the plurality of tests, one or more tests that are to be carried out on a centrifuged portion of the biological sample and one or more tests that are to be carried on a uncentrifuged portion of the biological sample, andfor each sample container of the plurality of sample containers, assigning, by the computing device, a respective set of tests of the plurality of tests to said each sample container, such that said respective set of tests assigned to said each sample container comprises either only tests that are to be carried out on a centrifuged portion of the biological sample or only tests that are to be carried out on an uncentrifuged portion of the biological sample. In particular each sample container of the plurality of container contains or is to contain a respective portion of the biological sample.

A first aspect of the present disclosure is related to a method for processing a biological sample with an automated laboratory system,comprising the steps:- loading a primary tube containing a primary biological sample comprising a pre-defined agent, e.g. Platelets;- performing a centrifugation of the primary biological sample;- transferring at least a part of the primary biological sample as a secondary biological sample into a secondary tube ;- performing a centrifugation of the secondary biological sample ;- providing a sample based on the centrifuged secondary biological sample.

A laboratory apparatus (100) for handling a sample tube (114) comprises a clamping device (102) having at least two clamping arms (108, 110) configured to be moved to a closed state for clamping the sample tube (114) arranged in a working space (W) therebetween and to be moved to an open state for releasing the sample tube (114) in the working space. Each clamping arm (108, 110) comprises a contact area (128, 130) configured to be in contact with the sample tube (114) in the closed state and to be out of contact with the sample tube (114) in the open state. At least one of the clamping arms (108, 110) further comprises a mechanically biased pushing member (140, 142) which is retractable against a biasing force upon contact with the sample tube (114) arranged in the working space (W) when the clamping arms (108, 110) are moved from the open state to the closed state, and which is extendable by the biasing force to push against the sample tube (114) and prevent the sample tube (114) from being pulled out of the working space (W) due to unintentional adhesion to the contact area (128, 130) when the clamping arms (108, 110) are moved from the closed state to the open state.

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The disclosure relates to a method (100) for determining a sample quality of a biological sample (2) inside an uncapped container (1), the method (100) comprising: - determining, by a data processing system (11), at least one sample color of the biological sample (2) based on a color image (9) showing at least part of a surface (6) of the biological sample (2) from a top view perspective on the container (1); and - determining, by the data processing system (11), the sample quality of the biological sample (2) based on a comparison of the determined at least one sample color with at least one reference color.

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A sample carrier (1) is configured to transport a sample along a track (120) of a sample transport system (100). The sample carrier (1) comprises a sample transport section (10) configured to hold and transport the sample, a conductive section (20), and a magnetic section (30). The magnetic section (30) is configured to induce an eddy current in an adjacent conductive section (20) of another element of the sample transport system (100) when there is a relative movement between the sample carrier (1) and this other element. The conductive section (20) is configured to experience eddy current induced by a magnetic section (30) of another element of the sample transport system (100) when there is a relative movement between the sample carrier (1) and this other element.

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