Novagraaf Technologies

A system for storing and querying BGP routing data. The system comprises a relational database (330) comprising a set of tables configured to store lossless compressed BGP routing data. The set of tables includes at least one indirection table. There is an indirection table per BGP route attribute among a set of at least one BGP route attribute, each indirection table storing distinct values of the considered BGP route attribute and associating each of the stored values with a unique identifier. The set of tables includes at least one main table storing BGP routing data sets, each BGP routing data set including at least one unique identifier from at least one indirection table but not the associated BGP route attribute value. The system comprises an API (320) configured to generate Database queries to the relational database. The API provides entry points corresponding respectively to primitive functions. The API is adapted to convert a call to any of the primitive functions into at least one database query to one or more of the set of tables.

The present invention relates to a coolant reservoir integrated module and an automobile. The coolant reservoir integrated module includes a flow channel plate and a coolant reservoir, where a multi-way valve is disposed on the flow channel plate, the flow channel plate is provided with external interfaces, at least two circuits are disposed in the flow channel plate, an inlet and an outlet of each of the at least two circuits are in communication with an interface of the multi-way valve and/or the external interfaces, and a water pump is correspondingly disposed in each of the at least two circuits; an exhaust and water replenishment passage is further disposed in the flow channel plate, the exhaust and water replenishment passage is internally divided into an exhaust section and a water replenishment section.

The present invention relates to sulfoxylated phenothiazine for use as a medicament.The present invention also relates to sulfoxylated phenothiazine for use in the treatment of painful sensations induced by neuropathy.The present invention also relates to a pharmaceutical composition comprising at least one sulfoxylated phenothiazine.

The invention belongs to the field of skin treatment. In particular, it relates to a topical cosmetic composition comprising tranexamic acid encapsulated in a liposome and a non-therapeutic cosmetic method comprising the application to the skin of said topical cosmetic composition. The topical cosmetic composition can be used in the treatment of melanin or hyperpigmented spot, brown spots, hyperpigmented spots such as ephelides, melasma, actinic lentigo, senile lentigo and post-inflammatory hyperpigmentation. In particular, the obtained results have demonstrated that, when topically applied, the composition advantageously improves the treatment of brown spots and/or hyperpigmentation spots.

Procédé (100) de caractérisation d'un matériau polycristallin par diffractométrie en vue d'une analyse cristallographique, caractérisé en ce que le procédé comprend en outre : - une étape de découpage (130) de la plage angulaire de déviation en différentes régions angulaires (IA1, IA2, IA3, IA4, IA5, IA6, IA7, IA8, IA9), et - dans l'itération : * une étape d'intégration (140) de chaque région angulaire (IA1, IA2, IA3, IA4, IA5, IA6, IA7, IA8, IA9) pour obtenir un résultat d'intégration pour chaque région angulaire (IA1, IA2, IA3, IA4, IA5, IA6, IA7, IA8, IA9), * une étape d'estimation (150) si tous les résultats d'intégration sont stables, et en ce que on utilise le résultat de l'étape d'estimation comme critère d'arrêt (150).

The present invention relates to a method of detecting and/or quantifying the presence of exons 5 and 6 of ANRIL (Antisense Noncoding RNA in the INK4 Locus) in a subject, comprising the following steps of:1) Preparation of total RNA from a biological sample of the subject,2) Conversion of RNA molecules into complementary DNA,3) Loop-mediated isothermal amplification using trans-exonic oligonucleotides that specifically amplify exons 5 and 6,4) Addition of Cas12a/RNA guides complexes, wherein RNA guide specifically targets exons 5 and 6 by base pairing,5) Addition of a reporter DNA probe,6) Detection of cleavage products, wherein detection of cleavage products reveals the presence of exons 5 and 6 of ANRIL, and7) possibly quantifying expression of exons 5 and 6 of ANRIL.The present invention also relates to a method for in vitro diagnosis of a cancer in a subject, to a method for in vitro prognosis a cancer in a subject to a kit for implementing the method and to a set of oligonucleotides.

The present application relates to a radio frequency system and a communication device. The radio frequency system may include: a transceiver circuit (10); a receiving circuit (20); a first coupling circuit (30), configured to support coupling of a transmit signal on a transceiver path and coupling of a reflected signal of the transmit signal, and output a first forward coupled signal and a first backward coupled signal; a second coupling circuit (40), configured to selectively turn on the receiving path and the coupling path, support coupling of the first forward coupled signal and coupling of the reflected signal, and output a second forward coupled signal and a second backward coupled signal; and, a processing circuit (50), configured to determine second impedance information of the receiving path according to the second forward coupled signal and the second backward coupled signal.

A radio frequency system (100) and an electronic device (1000). The radio frequency system includes a radio frequency transceiver module (10), a radio frequency front-end module (20), at least one antenna radiator (30), and at least one first low-noise amplification module (40). The radio frequency front-end module includes at least one transmission path (21) and at least one reception path (22). The transmission path is electrically connected to the radio frequency transceiver module, and the reception path is electrically connected to the radio frequency transceiver module. The first low-noise amplification module is connected between the antenna radiator and the reception path. When the first low-noise amplification module is in a first working state, it is conductive between the antenna radiator and the reception path, and when the first low-noise amplification module is in a first bypass state, it is short-circuited between the antenna radiator and the reception path.

The present invention relates to a method of detecting the presence of exon 8 of ANRIL (Antisense Non-coding RNA in the INK4 Locus) in a subject, comprising the following steps of:1) Preparation of total RNA from a biological sample of the subject,2) Conversion of RNA molecules into complementary DNA,3) Loop-mediated isothermal amplification using trans-exonic oligonucleotides that specifically produces an amplicon containing exon 8 fragment,4) Addition of Cas12a/RNA guide complexes, wherein RNA guide specifically targets exon 8-containing fragment by base pairing,5) Addition of a reporter DNA probe, and6) Detection of cleavage products,Wherein detection of cleavage products reveals the presence of exon 8 of ANRIL.The present invention also relates to a method for in vitro predicting in vitro the efficacy of a therapy targeting exon 8 of ANRIL in a subject, to a kit for implementing the method and to a set of oligonucleotides.

A computer implemented method of determining an environmental condition score of a geographical area, comprising: - obtaining (S1) image data (SID) of said geographical area, from satellite imagery (SAT) during for a given time period, - forming (S2) a cell grid across said image data of the geographical area, said cell grid comprising a plurality of cells (H); - processing (S3) the plurality of cells (H), comprising, for one cell of said plurality of cells: - determining (S32) a value of a vegetation condition sub-score (VEG<H>) for said cell; - determining (S33) a value of an infrastructure condition sub-score (INF<H>) for said cell; and - deriving (S35) a value of the environmental condition score (ENV<H>) for said cell at said time period from at least the vegetation condition sub-score and the infrastructure condition sub-score, and - providing (S4) the values of at least the environmental condition score (ENV<H>) for the plurality of cells corresponding to the given time period to a user through a human-machine interface.