Sysmex Patente

Disclosed is a smearing apparatus for use in an analysis system including an imaging apparatus configured to capture an image of a smear specimen, the smearing apparatus comprising: a supply unit configured to store a plurality of slide glasses, each assigned with slide identification information, and to supply the slide glasses one by one; an aspirator configured to aspirate a specimen contained in a specimen container; a smearer configured to smear the aspirated specimen onto the slide glass supplied from the supply unit; a stainer configured to stain the specimen smeared on the slide glass with a staining solution; a first reader configured to read specimen identification information assigned to the specimen container; a second reader configured to read the slide identification information; and a controller configured to digitally associate (A) the slide identification information of the slide glass on which the specimen is smeared and (B) the specimen identification information of the smeared specimen, thereby enabling the analysis system to identify the specimen based on the slide identification information.

Disclosed is a system for a surgical assistance robot configured to perform a surgical procedure on a patient using a surgical instrument attached to an arm, the system comprising: a console comprising (i) a hand controller configured to be manipulated by a surgeon to remotely control an operation of the surgical instrument, wherein the hand controller comprises a plurality of joints rotatable by a manipulation of the hand controller, and (ii) a viewer configured to display images captured by an endoscope, the images showing a surgical site of the patient and the operation of the surgical instrument; a storage configured to store (a) a video generated from the images which are captured during the surgical procedure and (b) a manipulation log representing a series of the manipulations of the hand controller during the surgical procedure, wherein the manipulation log comprises an angle of rotation of each of the joints according to the manipulation; and a transmitter configured to transmit, to the console, the video and the manipulation log stored in the storage, wherein the console is configured to rotate the joints according to the manipulation log in association with a playback of the video on the viewer for duplication of the manipulations by the surgeon during the surgical procedure.

[Problem] The problem is to provide a measure to enable a determination of whether a subject develops renal amyloidosis caused by proIAPP.[Solution] The above-mentoined problem is solved by measuring proIAPP in a biological sample from a subject, and using a result of the measuring as an indicator of proIAPP-type renal amyloidosis.

Disclosed is a specimen measurement system operable to optically perform a measurement on a specimen, the specimen measurement system comprising: a specimen analyzer configured to optically perform the measurement on the specimen, the specimen analyzer including: (i) a specimen suction part configured to suction the specimen, the specimen suction part comprising a nozzle to suction the specimen in a specimen container, a movement mechanism configured to move the nozzle into the specimen container and a pump configured to apply a negative pressure so that the nozzle suctions the specimen; (ii) a sample preparator configured to prepare a measurement sample by mixing the suctioned specimen and a reagent in a container; (iii) an optical detector configured to detect light from the prepared measurement sample; and (iv) a controller configured to control, according to control software, the specimen suction part, the sample preparator and the optical detector so that the specimen analyzer optically performs the measurement on the specimen, wherein the specimen analyzer analyzes, in order to obtain a measurement result, optical information which is derived from the detected light, and manages, according to management software, data relating to the specimen analyzer, wherein the data includes the measurement result; an imaging apparatus configured to capture images of blood cells in a smear of the specimen; and a computer capable of running an interface which interacts with application software programmed to utilize the data and the image, wherein the application software is independent of the specimen analyzer, wherein the interface executes operations including: (a) receiving a request from the application software; (b) retrieving, according to a predetermined rule, the images corresponding to the request, wherein the retrieved images are associated with metadata including morphological features of the blood cells; and (c) providing the retrieved images to the application software so that the application software displays, based on the metadata, a plurality of candidates indicating classification for a specific blood cell in the retrieved images that visually demonstrate the morphological features of the blood cells.

Disclosed is a measurement apparatus for blood samples including a reagent storage unit for first and second containers storing a diluent and a hemolytic agent, respectively, and a transport unit arranged above it. A measurement unit, also above the storage unit, includes a third container for a staining solution, chambers for preparing first and second measurement samples, and detectors for electrical and optical signals. The apparatus is configured to process 300 to 500 samples per hour for measurement orders including complete blood count and five-part white blood cell differential counting. A supply unit provides reagents to the measurement unit, and a control unit manages the operations. The supply unit is configured to continue supplying the diluent and the hemolytic agent while the first or second container is being replaced, ensuring uninterrupted measurement.

A sample analyzer (1) comprises: a measurement unit (2) measuring an analyte related to a dementia biomarker contained in a sample collected from a subject, and comprising: a sample dispenser, a first reagent dispenser, a second reagent dispenser, and a detector; a controller (101) comprising a processor and programmed to obtain a measurement value of the analyte based on the light detected by the detector; a storage (102) storing a reference value that specifies an outlier that may be caused by a factor other than dementia; and an output unit (103). The controller is programmed to execute a determination on whether the measurement value is specified as the outlier based on the measurement value and the reference value, generate an analysis result of the dementia biomarker based on the measurement value and a result of the determination, and output the analysis result of the dementia biomarker via the output unit.

Disclosed is a sample analysis system comprising: a plurality of measurement units, each configured to measure a sample to obtain a measurement result based on a measurement order including one or more measurement items; an identification information reader configured to read identification information of each of a plurality of first samples to be measured for diagnosis of a test subject by at least one of the plurality of measurement units; and a computer that is configured to: identify at least one of the plurality of first samples as a second sample used for a measurement for an inter-instrument difference evaluation, based on a timing to conduct the inter-instrument difference evaluation, wherein the timing is automatically determined by the computer; and control each of a plurality of target measurement units to measure the identified second sample based on a measurement order including one or more preset measurement items for the inter-instrument difference evaluation, and store a plurality of second measurement results of the second sample obtained from the plurality of target measurement units, for use in the inter-instrument difference evaluation, in the storage device in association with the identification information of the second sample.

Disclosed is a sample analysis system comprising: a plurality of measurement units, each configured to measure a sample to obtain a measurement result based on a measurement order including one or more measurement items; an identification information reader configured to read identification information of each of a plurality of samples to be measured by at least one of the plurality of measurement units; and a computer that comprises a storage device configured to store the measurement results. The computer is configured to perform operations for an inter-instrument difference evaluation, the operations comprising: interrogating a storage device to identify a set of a plurality of measurement results obtained from a plurality of target measurement units, the set of the plurality of measurement results matching a condition for use in the inter-instrument difference evaluation; and generating evaluation information for the inter-instrument difference evaluation based on the set of the plurality of measurement results identified from the storage device.

Disclosed is a specimen measurement apparatus including a measurement unit configured to measure a specimen, the specimen measurement apparatus including: control software configured to control the measurement unit; data management software configured to manage data regarding the measurement unit that operates under control by the control software; and an interface configured to allow application software capable of being added to a system including the specimen measurement apparatus, to utilize the data, wherein a function of the system is expanded by the application software added to the system.

A specimen container sorter (40) connected to a rack transportation path (1a) along which a rack (100) loaded with a specimen container (110) is transported in a first direction to a specimen analyzer (62), the specimen container sorter including: a container storage mechanism (49) configured to store a plurality of the specimen containers, each containing a specimen; a container transfer mechanism (45) configured to transfer, from the container storage mechanism to the rack, the specimen container containing the specimen to be analyzed by the specimen analyzer; and a rack sending mechanism (48) that is arranged below the container storage mechanism in a height direction of the specimen container sorter and is provided with a rack placement position (P12) where the rack that has received the specimen container transferred by the container transfer mechanism is placed, wherein the rack sending mechanism is configured to move the rack, in a second direction perpendicular to the first direction.

A specimen measurement system (1) comprises: a measurement unit (2) configured to measure a specimen; and a control unit (7) configured to analyze measurement data. The measurement unit (2) comprises: a first reagent container (230) accommodating a first reagent containing a substance that binds to an analyte in the specimen; a reagent holder (23) configured to hold the first reagent container (230); a specimen processor (21) configured to prepare a measurement sample by mixing the first reagent and the specimen; and a detector (22) configured to interrogate the analyte. The measurement unit (2) is arranged on a housing (24) that stores a second reagent container (240) containing a second reagent used for: (i) washing of a flow path of the measurement unit (2), (ii) dilution of the specimen, (iii) preparation of the measurement sample, and (iv) interrogation of the analyte of the measurement sample by the detector (22).

Disclosed is a system (1) for supporting health management of an athletic player, comprising: a measuring device (40) configured to measure myoglobin contained in blood of the player; and a server (10) configured to record an exercise load of the player and a measured value of the myoglobin of the player, wherein the server is configured to provide the exercise load of the player and the measured value of the player in response to a request from a terminal (20, 30).

Disclosed is a system including a measurement unit configured to measure a specimen, the system comprising: control software configured to control the measurement unit; data management software configured to manage data regarding the measurement unit that operates under control by the control software; and an interface configured to allow application software capable of being added to the system, to utilize the data, wherein a function of the system is expanded by the application software added to the system.

Disclosed is a data management system configured to manage data regarding a specimen measurement system including a measurement unit configured to measure a specimen and control software configured to control the measurement unit, the data management system including: data management software configured to manage data regarding the measurement unit that operates under control by the control software; and an interface configured to allow application software capable of being added to the specimen measurement system, to utilize the data, wherein a function of the specimen measurement system is expanded by the application software added to the specimen measurement system.

Disclosed is a sample measurement apparatus configured to measure a sample collected from a subject, comprising: a measurement unit configured to execute a measurement of the sample, the measurement including preparing a measurement sample from the sample and a reagent and detecting at least optical signals corresponding to cells in the measurement sample; and an analysis unit configured to analyze the cells at least according to the optical signals detected in the measurement of the sample by the measurement unit, wherein the measurement unit is operable to selectively perform a plurality of measurement operations including: (1) a first measurement operation that includes the measurement of the sample using a first reagent containing a first fluorescent dye that stains leukocytes for classification of leukocytes; (2) a second measurement operation that includes the measurement of the sample using a second reagent containing a second fluorescent dye that stains cells suspected of malaria infection; and (3) a third measurement operation that includes the measurement of the sample using the first reagent and the second reagent.

Disclosed is a specimen analysis apparatus (1A, 1B, 1C, 1) comprising: a measurement unit (20) configured to acquire optical information of cells contained in a specimen by irradiating the cells with a plurality of diffracted lights generated by causing light to be incident on a diffractive optical element (215); and an analysis unit (30) configured to analyze the optical information obtained by the measurement unit (20) using an artificial intelligence algorithm to acquire first information on leukemic cells contained in the specimen.

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Disclosed is an isolated monoclonal antibody comprising a heavy chain and a light chain, wherein the heavy chain comprises CDR1, CDR2 and CDR3 consisting of amino acid sequences set forth in SEQ ID NOs: 1, 2 and 3, respectively, and the light chain comprises CDR1, CDR2 and CDR3 consisting of amino acid sequences set forth in SEQ ID NOs: 4, 5 and 6, respectively.

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