Modiano, Gabriella Diana

A thermoplastic composition includes: (a) from about 10 wt% to about 90 wt% of a polycarbonate component including a polycarbonate homopolymer; (b) from about 5 wt% to about 20 wt% of a poly (carbonate-siloxane) copolymer having a siloxane content of from 10 wt% to 45 wt%; (c) from about 5 wt% to about 25 wt% of a glass fiber; and (d) at least one phosphorous-based flame retardant. The at least one phosphorous based flame retardant provides a total phosphorous content of from 0.22 wt% to 0.37 wt% to the composition. The combined weight percent value of all components does not exceed 100 wt%, and all weight percent values are based on the total weight of the composition. In some aspects the compositions have good UL94 flame retardant and high heat (e.g., ball pressure test) performance.

The invention pertains to a surgical tool control apparatus (100) comprising: a housing (1); a control assembly (2) comprising a first roller module (22a) and a second roller module (22b) connected to the housing (1) and movable relative to each other so that a first surgical tool (Ta) is gripped between the first roller module (22a) and the second roller module (22b); and a first clamping portion (6a) configured to clamp the first surgical tool (Ta) in a state in which the first surgical tool (Ta) is not gripped by the first roller module (22a) and the second roller module (22b).

Thermoplastic compositions include: a) from about 10 wt% to about 97 wt% of a first thermoplastic polymer component comprising polyetherimide (PEI), polyaryletherketone (PAEK), or a combination thereof; b) from about 0.1 wt% to about 10 wt% of a second chemically reactive polyetherimide (r-PEI) component that is different from the first polyetherimide component; and c) from about 2 wt% to about 10 wt% of a reactive polyolefin compatibilizer component. The combined weight percent value of all components does not exceed 100 wt%, and all weight percent values are based on the total weight of the composition. In certain aspects a molded sample of the composition has no delamination or plate-out as evaluated according to a visual observation.

This invention pertains to mutant Cas9 nucleic acids and proteins for use in CRISPR/Cas endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant Cas9 protein, wherein the isolated mutant Cas9 protein is active in a CRISPR/Cas endonuclease system, wherein the CRISPR/Cas endonuclease system displays reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system. The invention also includes isolated nucleic acids encoding mutant Cas9 proteins, ribonucleoprotein complexes and CRSPR/Cas endonuclease systems having mutant Cas9 proteins that display reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system.

Thermoplastic compositions include: a. from about 10 wt% to about 85 wt% of a polycarbonate component; b. from about 1 wt% to about 50 wt% of a polyester component; and c. from about 5 wt% to about 40 wt% of a polycarbonate-siloxane copolymer having a siloxane content of from 25 wt% to 60 wt%. The polycarbonate component in a. is different from the polycarbonate-siloxane copolymer in c. The composition comprises less than 1.0 wt% of a styrene-acrylonitrile encapsulated polytetrafluoroethylene (TSAN). The combined weight percent value of all components does not exceed 100 wt%, and all weight percent values are based on the total weight of the composition.

The present disclosure describes a novel security tag assembly, incorporating a unique geometric aperture pattern that enhances the assembly's security by requiring a specific tool for its removal while increasing resistance to unauthorized detachment. As such, the assembly effectively deters theft by complicating the removal process and potentially damaging the merchandise when tampered with improperly. Additionally, the assembly includes a non-visible wavelength emitter housed within a specially designed cavity that optimizes detectability while maintaining a compact form factor. This integration enables more effective monitoring of merchandise in retail environments, combining advanced security measures with efficient design to prevent unauthorized removal and to ensure the integrity of items tagged with the instant assembly.

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